Abstract
Hyperthermia involves the use of heat as a cancer treatment modality. It is occasionally used alone, but most often is employed in conjunction with ionizing radiation, and more recently, with chemotherapy (Dahl and Mella 1990). The goal of hyperthermia is to raise the temperature of the targeted region to therapeutic levels (approximately 42°–45°C) while keeping adjacent normal tissues at subtherapeutic temperatures.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Allen S, Kantor G, Bassen H, Rugerra P (1988) CDRH Rï phantom for hyperthermia systems evaluation. Int J Hyper thermia 4: 17–24
Anhalt D, Hynynen K, Roemer RB, Nethonson SM, Stea B Cassady JR (1982) Scanned ultrasound hyperthermia foi treating superficial disease. In: Gerner EW (ed) Hyperthermic oncology 1992, vol 1. Arizona Board of Regents, Tucson, p 3
Astrahan MA, Sapozink MD, Luxton G, Kampp TD, Petrovid Z (1989) A technique for combining microwave hyperthermia with intraluminal brachytherapy of the oesophagus. Int J Hyperthermia 5: 37–51
Atkinson WJ, Brezovich I A, Chakraborty DP (1984) Usable frequencies in hyperthermia with thermal seeds. IEEE Trans Biomed Eng 31: 70–75
Bach Andersen J, Baun A, Harmark K, Heinzl L, Raskmark P, Overgaard J (1984) A hyperthermia system using a new type ol inductive applicator. IEEE Trans Biomed Eng 31: 21–27
Bardati F, Bertero M, Mongiardo M, Solimini D (1987) Singular system analysis of the inversion of microwave radiometric data: applications to biological temperature retrieval. Inverse Problems 3: 347–370
Bassen H, Allen S, Herman B, Kantor G, Robinson R (1985) Quality assurance of RF and ultrasound cancer hyperthermia systems. Proc 7th Annual Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, New York, pp 346–351
Benkeser PJ, Frizzell LA, Ocheltree KB, Cain CA (1987) A tapered pha d ar y ultraso d transdu r r hyperthermia treatment. IEEE Trans Ultrason Ferroelec Freq Contr 34: 446–453
Benkeser PJ, Frizzell LA, Goss SA, Cain CA (1989) Analysis of a multielement ultrasound hyperthermia applicator. IEEE Trans Ultrason Ferroelec Freq Contr 36: 319–325
Berntsen S, Bach Andersen J, Gross E (1991) A general formulation of applied potential tomography. Radio Sei 26: 535–540
Bini M, Ignesti A, Millanta L, Olmi R, Rubino N, Vanni R (1984) The Polyacrylamide as a phantom material for electromagnetic hyperthermia studies. IEEE Trans Biomed Eng 31: 317–322
Bolomey JC, Hawley MS (1990) Noninvasive control of hyperthermia. In: Gautherie M (ed) Methods of hyperthermia control. Springer, Berlin Heidelberg New York, pp 35–111 (Clinical thermology, subseries thermotherapy)
Bowman RR (1976) A probe for measuring temperature in radio-frequency heated material. IEEE Trans Microwave Theory Tech MTT-24: 43–45
Brezovich IA (1988) Low frequency hyperthermia: capacitive and ferromagnetic seed metho. : Pali l , Hetl FW, Dewhirst MW (eds) Biological, physical and clinical aspects of hyperthermia. American Institute of Physics, New York, pp 82–110
Brezovich I A, Atkinson WJ, Chakraborty DP (1984) Temperature distributions in tumor models heated by self-regulating nickel-copper alloy thermoseeds. Med Phys 11: 145–152
Budihna M, Lesnicar H, Handl-Zeller L, Schreier K (1992) Animal experiments with interstitial water hyperthermia. In: Handl-Zeller (ed) Interstitial hyperthermia. Springer, Vienna, pp 155–163
Cain CA, Umemura SI (1986) Concentric-ring and sector vortex phased-array applicators for ultrasound hyperthermia. IEEE Trans Microwave Theory Tech MTT-34: 542–551
Cangellaris AC, Wright DB (1991) Analysis of the numerical error caused by the stair-stepped approximation of a conducting boundary in FDTD simulations of electromagnetic phenomena. IEEE Trans Antennas Propagat 39: 1518–1525
Carnochan P, Dickinson RJ, Joiner MC (1986) The practical use of thermocouples for temperature measurement in clinical hyperthermia. Int J Hyperthermia 2: 1–19
Casey JP, Bansal R (1986) The near field of an insulated dipole in a dissipative dielectric medium. IEEE Trans Microwave Theory Tech 34: 459–463
Chan AK, Sigelmann RA, Guy AW (1974) Calculations of therapeutic heat generated by ultrasound in fat-muscle-bone layers. IEEE Trans Biomed Eng 21: 280–284
Chan KW, Chou CK, McDougall JA, Luk KH, Vora NL, Forell BW (1989) Changes in heating patterns of interstitial microwave antenna arrays at different insertion depths. Int J Hyperthermia 5: 499–507
Chato JC (1990) Fundamentals of bioheat transfer. In: Gautherie M (ed) Thermal dosimetry and treatment planning. Springer, Berlin Heidelberg New York, pp 1–56 (Clinical thermology, subseries thermotherapy)
Chen JS, Poirier DR, Damento MA, Demer LJ, Biencaniello F, Cetas TC (1988) Development of Ni-4wt%Si thermoseeds for hyperthermia cancer treatment. J Biomater Res 22: 303–319
Chen JY, Gandhi OP (1992) Numerical simulation of annular-phased arrays of dipoles for hyperthermia of deep-seated tumors. IEEE Trans Biomed Eng 39: 209–216
Chitnalah A, Marchai C, Prieur G (1991) Sonde ultrasonore plane pour hyperthermic intracavitaire. Innovation et Technologie en Biologie et Medecine 12: 114–125
Chive M (1990) Use of microwave radiometry for hyperthermia monitoring radiometry and as a basis for thermal dosimetry. In: Gautherie M (ed) Methods of hyperthermia control. Springer, Berlin Heidelberg New York, pp 113–128 (Clinical thermology, subseries thermotherapy)
Chou CK, Chen GW, Guy AW, Luk KH (1984) Formulas for preparing phantom muscle tissue at various radiofrequencies. Bioelectromagnetics 5: 435–441
Chou CK, McDougall JA, Chan KW, Luk KH (1990) Effects of fat thickness on heating patterns of the microwave applicator MA-151 at 631 and 915 MHz. Int J Radiât Oncol Biol Physics 19: 1067–1070
Chou CK, McDougall JA, Chan KW, Luk KH (1991) Heating patterns of microwave applicators in inhomogeneous arm and thigh phantoms. Med Phys 18: 1164–1170
Christensen DA (1977) A new non-perturbing temperature probe using semiconductor band edge shift. J Bioeng 1: 541–545
Clegg ST, Roemer RB (1989) Towards the estimation of three-dimensional temperature fields from noisy temperature measurements during hyperthermia. Int J Hyperthermia 5:467–484
Clibbon KL, McCowen A, Hand JW (1993) SAR distributions in interstitial microwave antennas with a single dipole displacement. IEEE Trans Biomed Eng 40: 925–932
Conway J (1987) Electrical impedance tomography for thermal monitoring of hyperthermia treatment: an assessment using in vitro and in vivo measurements. Clin Phys Physiol 8 (Suppl A): 147–153
Corry PM, Barlogie B (1982) Clinical application of high frequency methods for local hyperthermia. In: Nussbaum GH (ed) Phys al aspects of hyperther a. Amer an Insti te of Physics, New York, pp 307–328
Corry PM, Jabboury K, Armour EP, Kong JS (1984) Human cancer treatment with ultrasound. IEEE Trans Sonics Ultrasonics 31: 444–455
Cosset JM (1990) Interstitial hyperthermia. In: Gautherie M (ed), Interstitial, endocavitary and perfusional hyperthermia, Springer, Berlin Heidelberg New York, pp 1–41
Crezee J, Mooibroek J, Lagendijk JJW (1993) Thermal model verification in interstitial hyperthermia. In: Seegenschmiedt MH, Sauer R (eds) Interstitial and intracavitary thermoradiotherapy. Springer, Heidelberg Berlin New York, pp 147–153
Dahl O, Mella O (1990) Hyperthermia and chemotherapeutic agents. In: Field SB, Hand JW (eds) An introduction to the practical aspects of clinical hyperthermia. Tay&or & Francis, London, pp 108–142
DeFord JA, Babbs CF, Patel UH, Bleyer MW, Marchosky JA, Moran CJ (1991) Effective interstitial hyperthermia. Int J Hyperthermia 7: 441–453
De Leeuw A AC, Crezee J, Lagendijk JJW (1993) Temperature and SAR measurements in deep-body hyperthermia with thermocouple thermometry. Int J Hyperthermia 9: 685–697
De Leeuw AAC, Lagendijk JJW, Van den Berg PM (1990) SAR distribution of the ‘coaxial TEM’ system with variable aperture width: measurements and model computations. Int J Hyperthermia 6: 445–451
De Leeuw AAC, Crezee J, Lagendijk JJW (1993) Temperature and SAR measurements in deep-body hyperthermia with thermocouple thermometry. Int J Hyperthermia 9: 685–697
Delannoy J, LeBihan D, Hoult DI, Levin RL (1990) Hyperthermia system combined with a MRI unit. Med Phys 17: 855–860
Denman DL, Foster AE, Cooper Lewis G et al. (1988) The distribution of power and heat produced by interstitial microwave antenna arrays. II. The role of antenna spacing and insertion depth. Int J Radiât Oncol Biol Phys 14: 537–545
Deurloo IKK, Visser AG, Morawska M, van Geel CAJF, van Rhoon CG, Levendag PC (1991) Applications of a capacitive-coupling interstitial hyperthermia system at 27 MHz: study of different applicator configurations. Phys Med Biol 36:119–132
Dewhirst MW, Philips TL, Samulski TV, et al. (1990) RTOG quality assurance guidelines for clinical trials using hyperthermia. Int J Radiat Oncol Biol Phys 18: 1249–1259
Dickinson RJ (1984) A non-rigid mosaic applicator for local ultrasound hyperthermia. In: Overgaard J (ed) Hyperthermic oncology 1984, vol 1. Taylor and Francis, London, pp 671–674
Dickinson RJ (1985) Thermal conduction errors of manganin-constantan thermocouple arrays. Phys Med Biol 30: 445–453
Diederich CJ, Hynynen K (1990) The development of intracavitary ultrasonic applicators for hyperthermia: a design and experimental study. Med Phys 17: 626–634
Diederich CJ, Hynynen K (1991) The feasibility of using electrically focused ultrasound arrays to induce deep hyperthermia via body cavities. IEEE Trans Ultrason Ferroelec Freq Contr 38: 207–219
Dorr LN, Hynynen K (1992) The effects of tissue heterogeneities and large blood vessels on the thermal exposure induced by short high-power ultrasound pulses. Int J Hyperthermia 8: 45–60
Doss JD (1982) Calculation of electric fields in conductive media. Med Phys 9: 566–573
Dunn F, Frizzell LA (1982) Bioeffects of ultrasound. In: Lehman JF (ed) Theraputic heat and cold, 3rd edn. Williams & Wilkins, Baltimore, pp 388–390
Dunscombe PB, Cetas TC, Connor WG, et al. (1989) Hyperthermia treatment planning (AAPM Report No 27). American Institute of Physics, New York
Durney CH (1990) Electromagnetic field propagation and interaction with tissue. In: Field SB, Hand JW (eds) An introduction to the practical aspects of clinical hyperthermia. Taylor & Francis, London, pp 242–274
Ebbini ES, Cain CA (1991a) Optimization of the intensity gain of multiple-focus phased-array heating patterns. Int J Hyperthermia 7: 953–973
Ebbini ES, Cain CA (1991b) Experimental evaluation of a prototype cylindrical section ultrasound hyperthermia phased-array applicator. IEEE Trans Ultrason Ferroelec Freq Contr 38: 510–520
Edmonds PD, Ross WC, Lee ER, Fessenden P (1985) Spatial distributions of heating by ultrasound transducers in clinical use indicated in a tissue-equivalent phantom. Proc 1985 IEEE Ultrasonics Symposium, New York, IEEE, pp 908–912
Emami B, Stauffer P, Dewhirst MW, et al. (1991) RTOG quality assurance guidelines for interstitial hyperthermia. Int J Radiat Oncol Biol Phys 20: 1117–1124
Fessenden P, Lee ER, Anderson TL, Strohbehn JW, Meyer JL, Samulski TV, Marmor JB (1984a) Experience with a multi-transducer ultrasound system for localized hyperthermia of deep tissues. IEEE Trans Biomed Eng 31: 126–135
Fessenden P, Lee ER, Samulski TV (1984b) Direct température measurement. Cancer Res (Suppl) 44:4799s–804s
Fessenden P, Kapp DS, Lee ER, Samulski TV (1988) Clinical microwave applicator design. In: Paliwal BR, Hetzel FW, Dewhirst MW (eds) Biological, physical and clinical aspects of hyperthermia. AAPM Medical Physics Monograph 16. American Institute of Physics, New York, pp 123–131
Fessenden P, Lee ER, Kapp DS, et al. (1993) Review of the Stanford experience developing non-focusing scanning and array surface microwave (MW) applicators. In: Gerner EW, Cetas TC (eds) Hyperthermic oncology 1992, vol 2. Arizona Board of Regents, Tucson, pp 183–186
Franconi C, Tiberio CA, Raganella L, Begnozzi L (1986) Low frequency RF twin dipole applicator for intermediate depth hyperthermia. IEEE Trans Microwave Theory Tech 34: 612–619
Furse CM, Iskander MF (1989) Three-dimensional electromagnetic power deposition in tumors using interstitial antenna arrays. IEEE Trans Biomed Eng 36: 977–986
Goffinet DR, Prionas SD, Kapp DS, et al. (1990) Interstitial 192Ir flexible catheter radiofrequency hyperthermia treatments of head and neck and recurrent pelvic carcinomas. Int J Radiât Oncol Biol Phys 18: 199–210
Gopal MK, Hand JW, Lumori MLD, Alkhairi S, Paulsen KD, Cetas TC (1992) Current sheet applicator arrays for superficial hyperthermia of chestwall lesions. Int J Hyperthermia 8: 227–240
Goss SA, Frizzell LA, Dunn F (1979) Ultrasonic absorption and attenuation in mammalian tissues. Ultrasound Med Biol 5: 181–186
Griffiths H, Ahmed A (1987) Applied potential tomography for non-invasive temperature mapping in hyperthermia. Clin Phys Physiol 8 (Suppl. A): 147–153
Gross EJ, Cetas TC, Stauffer PR, Liu RL, Lumori MLD (1990) Experimental assessment of phased-array heating of neck tumors. Int J Hyperthermia 6: 453–474
Hahn GM (1982) Hyperthermia and cancer. Plenum, New York
Haider SA, Chen ZP, Cetas TC, Roemer RB (1987) Interstitial ferromagnetic implant heating: practical guidelines for use. Proceedings 9th Annual Conference of IEEE Engineering in Medicine and Biology Society (vol 3). IEEE, New York, pp 1626–1628
Hall EJ (1982) Hyperthermia: an overview. In: Dethlefsen LA, Dewey WC (eds) Third international symposium: cancer therapy by hyperthermia, drugs and radiation (NCI Monograph 61), National Cancer Institute, Bethesda, pp xv–xvi
Hand JW (1990a) Biophysics and technology of electromagnetic hyperthermia. In: Gautherie M (ed) Methods of external hyperthermic heating. Springer, Berlin Heidelberg New York, pp 1–59 (Clinical thermology, subseries thermotherapy)
Hand JW (1990b) Quality assurance in hyperthermia. In: Field SB, Hand JW (eds) An introduction to the practical aspects of clinical hyperthermia. Taylor and Francis, London, pp 513–532
Hand JW, Hind AJ (1986) A review of microwave and RF applicators for localised hyperthermia. In: Hand JW, James JR (eds) Physical techniques in clinical hyperthermia. Research Studies Press, Letchworth, Hertfordshire, England, pp 98–148
Hand JW, Cheetham JL, Hind A J (1986) Absorbed power distributions from coherent microwave arrays for localized hyperthermia. IEEE Trans Microwave Theory Tech 34: 484–89
Hand JW, Lagendijk JJW, Andersen JB, Bolomey JC (1989) Quality assurance guidelines for ESHO protocols. Int J Hyperthermia 5: 421–428
Hand JW, Trembly BS, Prior MV (1992a) Physics of interstitial hyperthermia: radiofrequency and hot water tube techniques. In: Urano M, Douple E (eds) Hyperthermia and oncology, vol 3. Interstitial hyperthermia: physics, biology and clinical aspects. VSP, Utrecht, pp 99–134
Hand JW, Vernon CC, Prior MV (1992b) Early experience of a commercial scanned focused ultrasound hyperthermia system. Int J Hyperthermia 8: 587–607
Hand JW, Ebbinni E, O’Keeffe D, Israel D, Mohammadtaghi S (1994) An ultrasound phased array for use in intracavitary applicators for thermotherapy of prostatic diseases. Proc IEEE Ultrasonics 1993 Symposium, vol 2, IEEE, NY, pp 1225–1228
Handl-Zeller L, Handl O (1992) Simultaneous application of combined interstitial high-or low-dose rate irradiation with hot water hyperthermia. In: Handl-Zeller L (ed) Interstitial hyperthermia. Springer, Vienna, pp 165–170
Hartov A, Colacchio TA, Strohbehn JW, Ryan TP, Hoopes PJ (1993) Performance of an adaptive MIMO controller for a multiple-element ultrasound hyperthermia system. Int J Hyperthermia 9: 563–579
Heinzl L, Hornsleth SN, Raskmark P, Andersen JB (1990) Electromagnetic applicators. In: Field SB, Hand JW (eds) An introduction to the practical aspects of clinical hyperthermia. Taylor & Francis, London, pp 275–304
Hunt JW (1990) Principles of ultrasound used for generating localized hyperthermia. In: Field SB, Hand JW (eds) An introduction to the practical aspects of clinical hyperthermia. Taylor & Francis, London, pp 371–422
Hunt JW, Lalonde R, Ginsberg H, Urchuk S, Worthington A (1991) Rapid heating: critical theoretical assessment of thermal gradients found in hyperthermia treatments. Int J Hyperthermia 7: 703–718
Hurter W, Reinbold F, Lorenz WJ (1991) A dipole antenna for interstitial microwave hyperthermia. IEEE Trans Microwave Theory Tech 39: 1048–1054
Hynynen K (1990a) Biophysics and technology of ultrasound hyperthermia. In: Gautherie M (ed) Methods of external hyperthermic heating. Springer, Berlin Heidelberg New York, pp 61–115 (Clinical thermology, subseries thermotherapy)
Hynynen K (1990b) Hot spots created at skin-air interfaces during ultrasound hyperthermia. Int J Hyperthermia 6: 1005–1012
Hynynen K (1992) The feasibility of interstitial ultrasound hyperthermia. Med Phys 19: 979–987
Hynynen K, De Young D (1988) Temperature elevation at muscle-bone interface during scanned, focused ultrasound hyperthermia. Int J Hyperthermia 4: 267–279
Hynynen K, Edwards DK (1989) Temperature measurements during ultrasound hyperthermia. Med Phys 16: 618–626
Hynynen K, Watmough DJ, Mallard JR (1981) Design of ultrasonic transducers for local hyperthermia. Ultrasound Med Biol 7: 397–402
Hynynen K, Roemer R, Moros E, Johnson C, Anhalt D (1986) The effect of scanning speed on temperature and equivalent thermal exposure distributions during ultrasound hyperthermia in vivo. IEEE Trans Microwave Theory Tech 34: 552–559
Hynynen K, Roemer RB, Anhalt D, Johnson C, Xu ZK, Swindell W, Cetas TC (1987) A scanned focused, multiple transducer ultrasonic system for localised hyperthermia treatments. Int J Hyperthermia 3: 21–35 reier ressenaen ana jenrey w. nana
Hynynen K, Shimm D, Anhalt D, Stea B, Sykes H, Cassady JR, Roemer RB (1990) Temperature distributions during clinical scanned, focused ultrasound hyperthermia treatments. Int J Hyperthermia 6: 891–908
Hynynen K, Frederiksen F, Gautherie M, et al. (1992) Ultrasound hyperthermia (Tor Vergata Medical Physics Monograph Series, vol 2). Postgraduate School of Medical Physics, II University of Rome, Rome, pp 24–25
Ibbini MS, Cain CA (1989) A field conjugation method of direct synthesis of hyperthermia phased-array heating patterns. IEEE Trans Ultrason Ferroelec Freq Contr 36: 3–9
Ibbini MS, Cain CA (1990) The concentric-ring array for ultrasound hyperthermia: combined mechanical and electrical scanning. Int J Hyperthermia 6: 401–419
Ibbini MS, Ebbini ES, Cain CA (1990) N x N square-element ultrasound phased array applicator: simulated temperature distributions associated with directly synthesized heating patterns. IEEE Trans Ultrason Ferroelec Freq Contr 37: 491–500
Ibbott GS, Brezovich I, Fessenden P, et al. (1989) Performance evaluation of hyperthermia equipment (AAPM Report No 26). American Institute of Physics, New York
Iskander MF, Tumeh AM (1989) Design optimization of interstitial antennas. IEEE Trans Biomed Eng 36: 238–246
James BJ, Sullivan DM (1992) Direct use of CT scans for hyperthermia treatment planning. IEEE Trans Biomed Eng 39: 845–851
James BJ, Strohbehn JW, Mechling JA, Trembly BS (1989) The effect of insertion depth on the theoretical SAR patterns of 915 MHz dipole antenna arrays for hyperthermia. Int J Hyperthermia 5: 733–747
Johnson CC, Guy AW (1972) Nonionizing electromagnetic wave effects in biological materials and systems. Proc IEEE 60: 692–717
Johnson RH (1986) New type of compact electromagnetic applicator for hyperthermia in the treatment of cancer. Proc IEE 22: 591–593
Johnson RH, James JR, Hand JW, Hopewell JW, Dunlop PRC, Dickinson RJ (1984) New low-profile applicators for local heating of tissues. IEEE Trans Biomed Eng 31: 28–37
Johnson RH, Preece AW, Hand JW, James JR (1987) A new type of lightweight low-frequency electromagnetic hyperthermia applicator. IEEE Trans microwave Theory Tech 35:1317–1321
Jones KM, Mechling JA, Trembly BS, Strohbehn JW (1988) SAR distributions for 915 MHz interstitial microwave antennas used in hyperthermia for cancer therapy. IEEE Trans Biomed Eng 35: 851–857
Jones KM, Mechling J A, Strohbehn JW, Trembly BS (1989) Theoretical and experimental SAR distributions for interstitial dipole arrays used in hyperthermia. IEEE Trans Microwave Theory Tech 37: 1200–1209
Kapp DS, Prionas SD (1992) Experience with radiofrequency-local current field interstitial hyperthermia: biological rationale, equipment development and clinical results. In: Handl-Zeller L (ed) Interstitial hyperthermia. Springer, Vienna, pp 95–119
Kapp DS, Fressenden P, Samulski TV, et al. (1988) Stanford University institutional report. Phase I evaluation of equipment for hyperthermia treatment of cancer. Int J Hyperthermia 4: 75–115
Kapp DS, Peters Brown AN, Cox W, Cox RS (1993) Temperature differentials between treatment and pretreatment temperatures correlate with local control following radiotherapy and hyperthermia. Int J Radiat Oncol Biol Phys 27: 331–344
King RWP, Shen LC, Wu TT (1981) Embedded insulated antennas for communication and heating. Electromagnetics 1: 115–117
King RWP, Trembly BS, Strohbehn JW (1983) Electromagnetic field of an insulated antenna in a conducting or dielectric medium. IEEE Trans Microwave Theory Tech 31: 574–583
Kobayashi T, Kida Y, Tanaka T, Hattori K, Matsui M, Amemiya Y (1991) Interstitial hyperthermia for brain tumors using ferromagnetic implants with low Curie temperature. J Neuro-oncol 4: 153–163
Lagendijk JJW (1990) Thermal models: principles and implementation. In: Field SB, Hand JW (eds) An introduction to the practical aspects of clinical hyperthermia. Taylor & Frances, London, pp 478–512
Lagendijk JJW, Visser AG, Kaatee RSJP et al. (1994) The 27 MHz multi-electrode current source interstitial hyperthermia method. Activity, International Selectron Brachytherapy Journal 8(3)
Lagendijk JJW, De Leeuw AAC (1993) Technical note. Temperature errors using multi-sensor thermocouple probes with a common constantan wire. Int J Hyperthermia 9: 763–764
Lagendijk JJW, Hofman P, Schippr J (1988) Perfusion analysis in advanced breast carcinoma during hyperthermia. Int J Hyperthermia 4: 479–495
Lagendijk JJW, van den Berg PM, Hand JW, et al. (1992) Task Group Report 4: treatment planning and modelling in hyperthermia. (Tor Vergata Medical Physics Monograph Series) Postgraduate School of Medical Physics, II University of Rome, Rome
Lau RWM, Sheppard RJ, Howard G, Bleehen NM (1986) The modelling of biological systems in three dimensions using the time domain finite-difference method. II. The application and experimental evaluation of the method in hyperthermia applicator design. Phys Med Biol 31: 1257–1266
LeBihan D, Turner R, Moonen CTW, Pekar J (1991) Imaging of diffusion and microcirculation with gradient sensitization: design, strategy and significance. J Magn Reson Imaging 1: 7–28
Lee DJ, O’Neill MJ, Lam KS, Rostock R, Lam WC (1986) A new design of microwave interstitial applicator for hyperthermia with improved treatment volume. Int J Radiat Oncol Biol Phys 12: 2003–2008
Lee ER, Wilsey TR, Tarczy-Hornoch P, Kapp DS, Fessenden P, Lohrbach A, Prionas SD (1992) Body conformable 915 MHz microstrip array applicators for large surface area hyperthermia. IEEE Trans Biomed Eng 39: 470–483
Lele PP (1983) Physical aspects and clinical studies with ultrasonic hyperthermia. In: Storm FK (ed) Hyperthermia in cancer therapy. G.K. Hall, Boston, pp 333–367
Leopold KA, Dewhirst MW, Samulski TV, et al. (1993) Cumulative minutes with T90 greater than TEMP index is predictive of response of superficial malignancies to hyperthermia and radiation. Int J Radiat Oncol Biol Phys 25: 841–847
Leybovich LB, Emami B, Myerson R J, Straube WL, Sathiaseelan V (1991) Dual-antenna applicators for hyperthermia of tumors at intermediate depth. Int J Hyperthermia 7:455–464
Lin JC, Wang YJ (1987) Interstitial microwave antennas for thermal therapy. Int J Hyperthermia 3: 37–47
Lockwood JC, Willette JG (1973) High-speed method for computing the exact solution for the pressure variations in the nearfield of a baffled piston. J Acoust Soc Am 53: 735–741
Lyons M, Parker KJ (1988) Absorption and attenuation in soft tissues. II. Experimental results. IEEE Trans Ultrason Ferroelec Freq Contr 35: 511–521
Magin RL, Peterson AF (1989) Noninvasive microwave phased arrays for local hyperthermia: a review. Int J Hyperthermia 5: 429–450
Marchal C, Bey P, Metz R, Gaulard ML, Robert J (1982) Treatment of superficial human cancerous nodules by local ultrasound hyperthermia. Br J Cancer 45 (Suppl V): 243–245
McGough RJ, Ebbini ES, Cain CA (1992) Direct computation of ultrasound phased-array driving signals from a specified temperature distribution for hyperthermia. IEEE Trans Biomed Eng 39: 825–835
Mechling J A, Strohbehn JW, Ryan TP (1992) Three-dimensional theoretical temperature distributions produced by 915 MHz dipole antenna arrays with varying insertion depths in muscle tissue. Int J Radiat Oncol Biol Phys 22: 131–138
Mizushina S, Hamamura Y, Sugiura T (1989) A, method of solution for a class of inverse problems involving measurement errors and its application to medical microwave radiometry. IEEE MTT-S International Symposium Digest 171–174
Mizushina S, Shimizu T, Sugiura T (1992) Non-invasive thermometry with multi-frequency microwave radiometry. Front Med Biol Eng 4: 129–133
Morita N, Bach Andersen J (1982) Near field absorption in a circular cylinder from electric and magnetic line sources. Bioelectromagnetics 3: 253–274
Nasoni RL, Bowen T (1989) Ultrasonic speed as a parameter for non-invasive thermometry. In: Mizushina S (ed) Non-invasive temperature measurement. Gordon and Breach, New York, pp 95–107
NCRP (1981) NCRP Report No. 67. Radiofrequency electromagnetic fields: properties, quantities and units, biophysical interaction and measurements. National Council on Radiation Protection and Measurements, Washington, D.C., pp 25–44
NCRP (1986) NCRP Report No. 86. Biological effects and exposure criteria for radiofrequency electromagnetic fields. National Council on Radiation Protection and Measurements, Bethesda, Maryland, pp 38–39
Nikawa Y, Kikuchi M, Kaneko R, Matsuda T (1993) Design and evaluation of a lens applicator for a 430 MHz heating system. In: Gerner EW, Cetas TC (eds) Hyperthermic oncology 1992, vol 2. Arizona Board of Regents, Tucson, pp 199–202
Nussbaum GH, Side J, Rouhanizadeh N, et al. (1986) Manipulation of central axis heating patterns with a prototype, three-electrode capacitive device for deep-tumor hyperthermia. IEEE Trans Microwave Theory Tech 34: 620–625
Nussbaum GH, Straube WL, Drag MD, et al. (1991) Potential for localized, adjustable deep heating in soft-tissue environments with a 30-beam ultrasonic hyperthermia system. Int J Hyperthermia 7: 279–299
Nyborg WL, Steele RB (1985) Nearfield of a piston source of ultrasound in an absorbing medium. J Acoust Soc Am 78: 1882–1891
Ocheltree KB, Frizzell LA (1989) Sound field calculation for rectangular sources. IEEE Trans Ultrason Ferroelec Freq Contr 36: 242–248
Ocheltree KB, Benkeser PJ, Frizzell LA, Cain CA (1984) An ultrasonic phased array applicator for hyperthermia. IEEE Trans Sonics Ultrasonics 31: 526–531
Oleson JR, Samulski TV, Leopold KA, Clegg ST, Dewhirst MW, Dodge RK, George SL (1993) Sensitivity of hyperthermia trial outcomes to temperature and time: implications for thermal goals of treatment. Int J Radiat Oncol Biol Phys 25: 289–297
Overgaard J (1993) The future of hyperthermic oncology. In: Gerner EW, Cetas TC (eds) Hyperthermic oncology 1992, vol 2. Arizona Board of Regents, Tucson, pp 87–92
Paulsen KD (1990) Calculation of power deposition patterns in hyperthermia. In: Gautherie M (ed) Thermal dosimetry and treatment planning. Springer, Berlin Heidelberg New York, pp 57–117 (Clinical thermology, subseries thermotherapy)
Paulsen KD, Lynch DR, Stronbehn JW (1988) Three dimensional finite boundary and hybrid element solutions of the Maxwell equations for lossy dielectric media. IEEE Trans Microwave Theory Tech 36: 682–693
Paulsen KD, Strohbehn JW, Lynch DR (1985) Comparative theoretical performance for two types of hyperthermia systems. Int J Radiat Oncol Biol Phys 11: 1659–1671
Pennes HH (1948) Analysis of tissue and arterial blood temperatures in the human resting forearm. J Appl Physiol 1: 93–122
Picket-May MJ, Taflove A, Lin WC, Katz DS, Sathiaseelan V, Mital BB (1992) Initial results for automated computational modeling of patient-specific electromagnetic hyperthermia. IEEE Trans Biomed Eng 39: 226–236
Pounds DW, Britt RH (1984) Single ultrasonic crystal techniques for generating uniform temperature distributions in homogeneously perfused tissues. IEEE Trans Sonics Ultrasonics 31: 482–496
Prionas SD, Hahn GM (1985) Noninvasive thermometry using ultiple frequency-band ra om ry: a fe ibility study. Bioelectromagnetics 6: 391–404
Prionas SD, Kapp DS, Sokol JL, Fessenden P (1990) Absorption of ultrasound (US) near tissue to air interfaces. Abstracts of papers for the tenth annual meeting of the North American Hyperthermia Group, New Orleans, Louisiana, p 18
Prionas SD, Kapp DS, Goffient DR, Bagshaw MA, Ben-Yosef R, Sokol JL, Fessenden P (1993) Interstitial radiofrequency-induced hype her a. In: Gner EW, Tas TC (eds) Hyperthermic oncology 1992, vol 2. Arizona Board of Regents, Tucson, pp 249–253
Prionas SD, Kapp DS, Goffinet DR, Ben-Yosef R, Fessen P and Bagaw MA (1994) Thmomry of interstitial hyperthermia given as an adjuvant to brachytherapy for the treatment of carcinoma of the prostate. Int J Radiat Oncol Biol Phys 28(1): 151–162
Rine GP, Dewhirst MW, Cobb ED, Clegg ST, Coleman EN, Samulski TV, Wallen CA (1992) Feasibility of estimating the temperature distribution in a tumor heated by a waveguide applicator. Int J Radiat Oncol Biol Phys 23: 1009–1019
Robins HI, Dennis WH, Neville AJ, et al. (1985) A non-toxic system for 41.8°C whole body hyperthermia: results of a phase I study using a radiant heat device. Cancer Res 45: 3937–3944
Roemer RB (1990) Thermal dosimetry. In: Gautheric M (ed) Thermal dosimetry and treatment planning. Springer, Berlin Heidelberg New York, pp 119–214 (Clinical thermology, subseries thermotherapy)
Roemer RB, Cetas TC (1984) Applications of bioheat transfer simulations in hyperthermia. Cancer Res 44: 4788S-4798S
Roemer RB, Fletcher AM, Cetas TC (1985) Obtaining local SAR and blood perfusion data from temperature measurements: steady-state and transient techniques compared. Int J Radiat Oncol Biol Phys 11: 1539–1550
Roos D, Hugander A (1988) Microwave interstitial applicators with improved longitudinal heating patterns. Int J Hyperthermia 4: 609–615
Ryan TP (1991) Comparison of six microwave antennas for hyperthermia treatment of cancer: SAR results for single antennas and arrays. Int J Radiat Oncol Biol Phys 21:403–413
Ryan TP, Mechling J A, Strohbehn JW (1990) Absorbed power deposition for various insertion depths for 915 MHz interstitial dipole antenna arrays: experiment versus theory. Int J Radiat Oncol Biol Phys 19: 377–387
Ryan TP, Hoopes PJ, Taylor JH, Strohbehn JW, Roberts DW, Douple EB, Coughlin CT (1991) Experimental brain hyperthermia: techniques for heat delivery and thermometry. Int J Radiat Oncol Biol Phys 20: 739–750
Samulski TV, Clegg ST, Das S, MacFall J, Prescott DM (1994) Application of new technology in clinical hyperthermia. Int J Hyperthermia 10: 389–394
Samulski TV, Fessenden P (1990) Thermometry in therapeutic hyperthermia. In: Gautherie M (ed) Methods of hyperthermia control. Springer, Berlin Heidelberg New York, pp 1–34 (Clinical thermology, subseries thermotherapy)
Samulski TV, Chopping PT, Haas B (1982) Photoluminescent thermometry based on europium-activated calcium sulfide. Phys Med Biol 27: 107–114
Samulski TV, Lyons BE, Britt RH (1985) Temperature measurements in high thermal gradients. II. Analysis of conduction effects. Int J Radiat Oncol Biol Phys 11: 963–971
Samulski TV, Kapp DS, Fessenden P, Lohrbach A (1987a) Heating deep seated eccentrically located tumors with an annular phased array system: a comparative clinical study using two annular array operating configurations. Int J Radiat Oncol Biol Phys 13: 83–94
Samulski TV, Fessenden P, Valdagni R, Kapp DS (1987b) Correlations of thermal washout rate, steady-state temperatures and tissue type in deep seated recurrent or metastatic tumors. Int J Radiat Oncol Biol Phys 13: 907–916
Samulski TV, Fessenden P, Lee ER, Kapp DS, Tanabe E, McEuen A (1990a) Spiral microstrip hyperthermia applicators: technical design and clinical performance. Int J Radiat Oncol Biol Phys 18: 233–242
Samulski TV, Grant WJ, Oleson JR, Leopold KA, Dewhirst MW, Vallario P, Blivin J (1990b) Clinical experience with a multielement ultrasonic hyperthermia system: analysis of treatment temperatures. Int J Hyperthermia 6: 909–922
Samulski TV, MacFall J, Zhang Y, Grant W, Charles C (1992) Non-invasive thermometry using magnetic resonance diffusion imaging: potential for application in hyperthermic oncology. Int J Hyperthermia 8: 819–829
Sandhu TS, Kowal HS, Johnson RJR (1978) The development of microwave hyperthermia applicators. Int J Radiat Oncol Biol Phys 4: 515–519
Sapozink MD, Corry PM, Kapp DS, et al. (1991) Quality assurance guidelines for clinical trials using hyperthermia for deep seated malignancy. Int J Radiat Oncol Biol Phys 20: 1109–1115
Sathiaseelan V, Leybovich L, Emami MS, Stauffer P, Straube W (1991) Characteristics of improved microwave interstitial antennas for local hyperthermia. Int J Radiat Oncol Biol Phys 20: 531–539
Satoh T, Stauffer PR, Fike JR (1988) Thermal distribution studies of helical coil microwave antennas for interstitial hyperthermia. Int J Radiat Oncol Biol Phys 15: 1209–1218
Schneider C, van Dijk JDP (1991) Visualization with a matrix of LEDs of interference effects from a radiative four applicator hyperthermia system. Int J Hyperthermia 7: 355–366
Schreier K, Budhina M, Lesnicar H, et al. (1990) Preliminary studies of interstitial hyperthermia using hot water. Int J Hyperthermia 6: 431–434
Sekins KM, Emery AF (1982) Thermal science for physical medicine. In: Lehmann JF (ed) Therapeutic heat and cold, 3rd edn. Williams & Wilkins, Baltimore, pp 70–132
Seppi E, Shapiro E, Zitelli L, Henderson S, Wehlau A, Wu G, Dittmer C (1985) A large aperture ultrasonic array system for hyperthermia treatment of a deep seated tumors. In: Proceedings IEEE Ultrasonics Symposium, IEEE, New York, pp 942–948
Shrivastava P, Luk K, Oleson JR, et al. (1989) Hyperthermia quality assurance guidelines. Int J Radiat Oncol Biol Phys 16: 571–587
Storm FK, Harrison WH, Elliott RS, Kaiser LR, Silberman AW, Morton DL (1981) Clinical radiofrequency hyperthermia by magnetic loop induction. J Microwave Power 16: 179–184
Strohbehn JW (1982) Theoretical temperature distributions forsolenoidal-type hyperthermia systems. Med Phys 9: 673–682
Strohbehn JW, Roemer RB (1984) A survey of computer simulations of hyperthermia treatments. IEEE Trans Biomed Eng 31: 136–149
Strohbehn JW, Paulsen KD, Lynch DR (1986) Use of the finite element method in computerized thermal dosimetry. In: Hand JW, James JR (eds) Physical techniques in clinical hyperthermia. Research Studies Press, Letchworth, Hertfordshire, England, pp 383–451
Strutt JW (1945) Theory of sound, vol 2. Dover, New York
Sugimachi K, Matsuda H (1990) Experimental and clinical studies of hyperthermia for carcinomas of the esophagus. In: Gautherie M (ed) Interstitial, endocavitary and perfusional hyperthermia. Springer, Berlin Heidelberg New York, pp 59–76
Sullivan D (1990) Three-dimensional computer simulation in deep regional hyperthermia using the finite-difference time-domain method. IEEE Trans Microwave Theory Tech 38: 204–211
Sullivan DM (1992) A frequency-dependent FDTD method for biological applications. IEEE Trans Microwave Theory Tech 40: 532–539
Sullivan DM, Buechler D, Gibbs FA (1992) Comparison of measured and simulated data in an annular phased array using an inhomogeneous phantom. IEEE Trans Microwave Theory Tech 40: 600–604
Sullivan DM, Ben-Yosef R, Kapp DS (1993) Standford 3-D hyperthermia treatment planning system. Int J Hyperthermia 9: 627–643
Swindell W (1986) Ultrasonic hyperthermia. In: Hand JW, James JR (eds) Physical techniques in clinical hyperthermia. Research Studies Press, Letchworth, Hertfordshire, England, pp 288–326
Tanabe E, McEuen A, Norris CS, Fessenden P, Samulski TV (1983) A multi-element microstrip antenna for local hyperthermia. IEEE MTT-S International Microwave Symposium Digest, pp 183–185
Tarczy-Hornoch P, Lee ER, Sokol JL, Prionas SD, Lohrbach AW, Kapp DS (1992) Automated mechanical thermometry probe mapping systems for hyperthermia. Int J Hyperthermia 8: 543–554
Trembly BS (1985) The effects of driving frequency and antenna length on power deposition within a microwave antenna array used for hyperthermia. IEEE Trans Microwave Theory Tech 32: 152–157
Trembly BS, Wilson AH, Sullivan MJ, Stein AD, Wong TZ, Strohbehn JW (1986) Control of the SAR pattern within an interstitial mocrowave array through variation of antenna driving phase. IEEE Trans Microwave Theory Tech 34: 568–571
Trembly BS, Douple EB, Hoopes PJ (1991) The effect of air cooling on the radial temperature distribution of a single microwave hyperthermia antenna in vivo. Int J Hyperthermia 7: 343–354
Tumeh AM, Iskander MF (1989) Performance comparison of available interstitial antennas for microwave hyperthermia. IEEE Trans Microwave Theory Tech 37: 1126–1133
Turner PF (1984) Regional hyperthermia with an annular phased array. IEEE Trans Biomed Eng 31: 106–114
Turner PF (1986) Interstitial equal-phased arrays for EM hyperthermia. IEEE Trans Microwave Theory Tech 34: 572–578
Umemura S, Cain CA (1989) The sector-vortex phased array: acoustic field synthesis for hyperthermia. IEEE Trans Ultrason Ferroelec Freq Contr 36: 249–257
Umemura S, Cain C A (1992) Acoustical evaluation of a prototype sector-vortex phased-array applicator. IEEE Trans Ultrason Ferroelec Freq Contr 39: 32–38
van der Zee J (1988) ESHO 5–88: protocol for phase III trial involving reirradiation of recurrent breast cancer with or without hyperthermia. Dr. Daniel den Hoed Cancer Center, Rotterdam
van der Zee J, van Rhoon GC (1993) Eindverslag Ontwikkelingsgeneeskunde project OG 89–23: de waarde van hyperthermic bij toevoeging aan radiotherapie bij de behandeling van inoperabele en stralingsresistente tumoren. A report to the Dutch Ministry of Health Care
van Dijk JDP, Schneider C, van Os R, Blank LE, Gonzalez DG (1990) Results of deep body hyperthermia with large waveguide radiators. Adv Exp Med Biol 267: 315–319
van Rhoon GC, Rietveld PJM, Broekmeyer-Reurink MP, Verloopvan’t Hof EM, van der Ploeg SK, van der Zee J (1993) DUD A 433 MHz waveguide applicator system with an improved effective field size for hyperthermia treatment of superficial tumors on the chest wall. In: Gerner EW, Cetas TC (eds) Hyperthermic oncology 1992, vol 2. Arizona Board of Regents, Tucson, pp 187–190
Vernon CC, Hand JW, Field SB, Machin D (1990) A study of the use of hyperthermia in the treatment of breast and head and neck tumours: a MRC multi-centre phase III trial. Trial closed for accrual Dec 1993. Results to be published in 1994
Visser AG, Deurloo IKK, Levendag PC, Ruifrok ACC, Cornet B, van Rhoon GC (1989) An interstitial hyperthermia system at 27 MHz. Int J Hyperthermia 5: 265–276
Visser AG, Chive M, Hand JW, et al. (1992) Interstitial and intracavitary hyperthermia: a task group report of the European Society for Hyperthermic Oncology, Postgraduate School of Medical Physics, University of Rome. Tor Vergata, Rome
Visser AG, Kaatee RSJP, Levendag PC (1993) Radiofrequency techniques for interstitial hyperthermia. In: Seegenschmiedt MH, Sauer R (eds) Interstitial and intracavitary thermoradiotherapy. Springer, Berlin Heidelberg New York, pp 35–41
Waterman FM, Hoh LLS (1994) A rcommended revision in the RTOG thermometry guidelines for hyperthermia administered by ultrasound. Int J Hyperthermia
Waterman FM, Leeper JB (1990) Temperature artifacts produced by thermocouples used in conjunction with 1 and 3 MHz ultrasound. Int J Hyperthermia 6: 383–399
Wickersheim KA (1986) A new fiberoptic thermometry system for use in medical hyperthermia. SPIE Proceedings, vol 713
Williams RA (1983) Ultrasound: biological effects and potential hazards. Academic, London, pp 107–110
Wu A, Watson ML, Sternick ES, Bielawa RJ, Carr KL (1987) Performance characteristics of a helical coil microwave interstitial antenna for local hyperthermia. Med Phys 14: 235–237
Wust P, Fahling H, Nadobny J, Felix R, Seebass M (1993) Potential of radiofrequency hyperthermia: planning, optimization, technological development. In: Gerner EW, Cetas TC (eds) Hyperthermia oncology 1992 vol 2. Arizona Board of Regents, pp 65–72
Young IR, Hand JW, Oatridge A, Prior M, Forse G (1994) Further observations of the measurement of tissue Tl to monitor temperature in vivo by MR. Magn Reson Med 31: 342–345
Yuan X, Strohbehn W, Lynch DR, Johnsen M (1990) Theoretical investigation of a phased-array hyperthermia system with moveable aperatures. Int J Hyperthermia 6: 227–240
Zemanek J (1971) Beam behaviour within the nearfield of a vibrating piston. J Acoust Soc Am 49: 181–191
Zhang Y, Dubai NV, Takemoto-Hambleton R, Joines WT (1988) The determination of the electromagnetic field and SAR pattern of an interstitial applicator in a dissipative medium. IEEE Trans Microwave Theory Tech 36: 1438–1443
Zhang Y, Joines WT, Oleson JR (1990a) The calculated and measured temperature distribution of a phased interstitial antenna array. IEEE Trans Microwave Theory Tech 38: 69–77
Zhang Y, Joines WT, Oleson JR (1990b) Microwave hyperthermia induced by a phased interstitial antenna array. IEEE Trans Microwave Theory Tech 38: 217–221
Zhang Y, Joines WT, Oleson JR (1991a) Heating patterns generated by phase modulation of a hexagonal array of interstitial antennas. IEEE Trans Biomed Eng 38: 92–97
Zhang Y, Joines WT, Oleson JR (1991b) Prediction of heating patterns of a microwave interstitial array at various insertion depths. Int J Hyperthermia 7: 197–207
Zhou LJ, Fessenden P (1993) Automation of temperature control for large-array microwave surface applicators. Int J Hyperthermia 9: 479–490
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Fessenden, P., Hand, J.W. (1995). Hyperthermia Therapy Physics. In: Smith, A.R. (eds) Radiation Therapy Physics. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03107-0_14
Download citation
DOI: https://doi.org/10.1007/978-3-662-03107-0_14
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-03109-4
Online ISBN: 978-3-662-03107-0
eBook Packages: Springer Book Archive