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Pathogenesis of Wound Infections

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Wound Healing and Skin Physiology

Abstract

The introduction of antibiotics has caused a decline in surgical infections, and gram-negative organisms replaced Staphylococcus aureus as the major nosocomial pathogen during the 1960s and 1970s in the industrialized world. However, during the last decade we have encountered a revival of S. aureus as a major wound pathogen, partly because of the emergence of multiple antibiotic resistant strains and methicillin-resistant S. aureus (MRSA). In biomaterial-associated infections, i.e., infections in intravascular and intraperitoneal catheters, joint and vascular prostheses, coagulase-negative staphylococci, mainly S. epidermidis, are the most important pathogens [9, 106]. They may also cause wound infections, and multiple antibiotic resistant strains are commonly isolated in hospital environments. In burn wound infections Pseudomonas aeruginosa is well established as a primary pathogen, as is the fungus Candida albicans [33]. Groups A, C and G streptococci have, throughout the decades, been the primary pathogens of different kinds of wound infections.

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Authors and Affiliations

  1. Department of Medical Microbiology, Sölvegatan 23, S-223 62, Lund, Sweden

    T. Wadström & Å. Ljungh

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  1. T. Wadström
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  2. Å. Ljungh
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Editors and Affiliations

  1. Dermatologische Klinik im St. Josef-Hospital, Ruhr-Universität, Gudrunstr. 56, 44791, Bochum, Germany

    Peter Altmeyer , Klaus Hoffmann  & Stephan el Gammal ,  & 

  2. ConvaTec Wound Healing Institute, Deeside, Clwyd, CH5 2NU, UK

    Jerry Hutchinson

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© 1995 Springer-Verlag Berlin Heidelberg

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Wadström, T., Ljungh, Å. (1995). Pathogenesis of Wound Infections. In: Altmeyer, P., Hoffmann, K., el Gammal, S., Hutchinson, J. (eds) Wound Healing and Skin Physiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77882-7_38

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  • DOI: https://doi.org/10.1007/978-3-642-77882-7_38

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-56124-8

  • Online ISBN: 978-3-642-77882-7

  • eBook Packages: Springer Book Archive

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