Abstract
Early detection of pathological changes in tissue is significant especially for cancer diagnosis. In many cases it decreases tumor development or completely cures patient. The most reliable method of cancer diagnosis currently used is microscopic cytological or histology analysis, which requires wide knowledge and experience form doctors. Polarimetric method presented in this article allows observations of cells or tissue sectors in light of different polarization degrees, under the microscope. Genesis of pathological changes entails in remodeling of tissue structure. Due to structure changes and rebuilding of collagen molecules, tissue reveals different optical properties than physiologically normal tissue. One of those is birefringence. Described work was focused on elaborating polarimetric method for testing optical characteristics of tissue samples, choosing the proper method for polarimetric image analysis and finding such optical characteristics, which will show correlation with cancer occurrence. The scientist aim was to extend knowledge of relation between arrangement of birefrigent elements and physiological state of tissue.
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Golnik, N., Pałko, T., Żebrowska, E. (2010). System for Gaining Polarimetric Images of Pathologically Changed Tissues and Testing Optical Characteristics of Tissue Samples. In: Brezina, T., Jablonski, R. (eds) Recent Advances in Mechatronics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-05022-0_70
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DOI: https://doi.org/10.1007/978-3-642-05022-0_70
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