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Wound Closure and Postoperative Hernia Prevention Strategies

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Hernia Surgery

Abstract

Closure of the laparotomy wound is the first and most important time point for prevention of postoperative hernia. Abdominal wound dehiscence and incisional hernia are major complications, associated with high morbidity and even mortality. Various risk models have been developed for both conditions, consisting of both patient and surgery-related risk factors. Surgical risk factors that can be influenced by surgeons include type of incision, type of suture material, and type of suture technique. In order to prevent incisional hernia in the midline incision, it is advocated to suture the abdominal wall continuously in a mass closure technique. Slowly absorbable sutures should be used with a suture length to wound length ratio of at least 4:1 using small stitches (5–8 mm) with small inter suture distances (5 mm). Currently, there is not enough evidence to support the use of retention sutures or abdominal binders to prevent incisional hernia. In high-risk patients, e.g., with obesity or abdominal aortic aneurysms, it should be considered to use prophylactic mesh (in onlay or sublay position). Prophylactic mesh in onlay position has been associated with increased incidence of seroma formation.

*Contributed equally to this chapter

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References

  1. Timmermans L, Eker HH, Steyerberg EW, Jairam A, de Jong D, Pierik EG, et al. Short-term results of a randomized controlled trial comparing primary suture with primary glued mesh augmentation to prevent incisional hernia. Ann Surg. 2014;261(2):276–81.

    Article  Google Scholar 

  2. Strzelczyk JM, Szymanski D, Nowicki ME, Wilczynski W, Gaszynski T, Czupryniak L. Randomized clinical trial of postoperative hernia prophylaxis in open bariatric surgery. Br J Surg. 2006;93(11):1347–50.

    Article  CAS  PubMed  Google Scholar 

  3. Burger JW, van’t Riet M, Jeekel J. Abdominal incisions: techniques and postoperative complications. Scand J Surg. 2002;91(4):315–21.

    CAS  PubMed  Google Scholar 

  4. Dubay DA, Franz MG. Acute wound healing: the biology of acute wound failure. Surg Clin North Am. 2003;83(3):463–81.

    Article  PubMed  Google Scholar 

  5. Van’t Riet M, De Vos Van Steenwijk PJ, Bonjer HJ, Steyerberg EW, Jeekel J. Incisional hernia after repair of wound dehiscence: incidence and risk factors. Am Surg. 2004;70(4):281–6.

    Google Scholar 

  6. Carlson MA. Acute wound failure. Surg Clin North Am. 1997;77(3):607–36.

    Article  CAS  PubMed  Google Scholar 

  7. Gislason H, Gronbech JE, Soreide O. Burst abdomen and incisional hernia after major gastrointestinal operations—comparison of three closure techniques. Eur J Surg. 1995;161(5):349–54.

    CAS  PubMed  Google Scholar 

  8. Gislason H, Viste A. Closure of burst abdomen after major gastrointestinal operations—comparison of different surgical techniques and later development of incisional hernia. Eur J Surg. 1999;165(10):958–61.

    Article  CAS  PubMed  Google Scholar 

  9. Bevis PM, Windhaber RA, Lear PA, Poskitt KR, Earnshaw JJ, Mitchell DC. Randomized clinical trial of mesh versus sutured wound closure after open abdominal aortic aneurysm surgery. Br J Surg. 2010;97(10):1497–502.

    Article  CAS  PubMed  Google Scholar 

  10. Hidalgo MP, Ferrero EH, Ortiz MA, Castillo JM, Hidalgo AG. Incisional hernia in patients at risk: can it be prevented? Hernia. 2011;15(4):371–5.

    Article  CAS  PubMed  Google Scholar 

  11. El-Khadrawy OH, Moussa G, Mansour O, Hashish MS. Prophylactic prosthetic reinforcement of midline abdominal incisions in high-risk patients. Hernia. 2009;13(3):267–74.

    Article  CAS  PubMed  Google Scholar 

  12. Caro-Tarrago A, Olona Casas C, Jimenez Salido A, Duque Guilera E, Moreno Fernandez F, Vicente GV. Prevention of incisional hernia in midline laparotomy with an onlay mesh: a randomized clinical trial. World J Surg. 2014;38(9):2223–30.

    Article  CAS  PubMed  Google Scholar 

  13. Llaguna OH, Avgerinos DV, Nagda P, Elfant D, Leitman IM, Goodman E. Does prophylactic biologic mesh placement protect against the development of incisional hernia in high-risk patients? World J Surg. 2011;35(7):1651–5.

    Article  CAS  PubMed  Google Scholar 

  14. Veljkovic R, Protic M, Gluhovic A, Potic Z, Milosevic Z, Stojadinov A. Prospective clinical trial of factors predicting the early development of incisional hernia after midline laparotomy. J Am Coll Surg. 2010;210(2):210–9.

    Article  PubMed  Google Scholar 

  15. Brown SR, Goodfellow PB. Transverse verses midline incisions for abdominal surgery. Cochrane Database Syst Rev. 2005;(4):CD005199.

    Google Scholar 

  16. Halm JA, Lip H, Schmitz PI, Jeekel J. Incisional hernia after upper abdominal surgery: a randomised controlled trial of midline versus transverse incision. Hernia. 2009;13(3):275–80.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Seiler CM, Deckert A, Diener MK, Knaebel HP, Weigand MA, Victor N, et al. Midline versus transverse incision in major abdominal surgery: a randomized, double-blind equivalence trial (POVATI: ISRCTN60734227). Ann Surg. 2009;249(6):913–20.

    Article  PubMed  Google Scholar 

  18. Fassiadis N, Roidl M, Hennig M, South LM, Andrews SM. Randomized clinical trial of vertical or transverse laparotomy for abdominal aortic aneurysm repair. Br J Surg. 2005;92(10):1208–11.

    Article  CAS  PubMed  Google Scholar 

  19. Grantcharov TP, Rosenberg J. Vertical compared with transverse incisions in abdominal surgery. Eur J Surg. 2001;167(4):260–7.

    Article  CAS  PubMed  Google Scholar 

  20. Proske JM, Zieren J, Muller JM. Transverse versus midline incision for upper abdominal surgery. Surg Today. 2005;35(2):117–21.

    Article  PubMed  Google Scholar 

  21. Armstrong CP, Dixon JM, Duffy SW, Elton RA, Davies GC. Wound healing in obstructive jaundice. Br J Surg. 1984;71(4):267–70.

    Article  CAS  PubMed  Google Scholar 

  22. Stone HH, Hoefling SJ, Strom PR, Dunlop WE, Fabian TC. Abdominal incisions: transverse vs vertical placement and continuous vs interrupted closure. South Med J. 1983;76(9):1106–8.

    Article  CAS  PubMed  Google Scholar 

  23. Greenall MJ, Evans M, Pollock AV. Midline or transverse laparotomy? A random controlled clinical trial. Part I: influence on healing. Br J Surg. 1980;67(3):188–90.

    Article  CAS  PubMed  Google Scholar 

  24. Riou JP, Cohen JR, Johnson Jr H. Factors influencing wound dehiscence. Am J Surg. 1992;163(3):324–30.

    Article  CAS  PubMed  Google Scholar 

  25. van’t Riet M, Steyerberg EW, Nellensteyn J, Bonjer HJ, Jeekel J. Meta-analysis of techniques for closure of midline abdominal incisions. Br J Surg. 2002;89(11):1350–6.

    Article  Google Scholar 

  26. Niggebrugge AH, Trimbos JB, Hermans J, Steup WH, Van De Velde CJ. Influence of abdominal-wound closure technique on complications after surgery: a randomised study. Lancet. 1999;353(9164):1563–7.

    Article  CAS  PubMed  Google Scholar 

  27. Weiland DE, Bay RC, Del Sordi S. Choosing the best abdominal closure by meta-analysis. Am J Surg. 1998;176(6):666–70.

    Article  CAS  PubMed  Google Scholar 

  28. Berretta R, Rolla M, Patrelli TS, Piantelli G, Merisio C, Melpignano M, et al. Randomised prospective study of abdominal wall closure in patients with gynaecological cancer. Aust N Z J Obstet Gynaecol. 2010;50(4):391–6.

    Article  PubMed  Google Scholar 

  29. Wissing J, van Vroonhoven TJ, Schattenkerk ME, Veen HF, Ponsen RJ, Jeekel J. Fascia closure after midline laparotomy: results of a randomized trial. Br J Surg. 1987;74(8):738–41.

    Article  CAS  PubMed  Google Scholar 

  30. Gupta H, Srivastava A, Menon GR, Agrawal CS, Chumber S, Kumar S. Comparison of interrupted versus continuous closure in abdominal wound repair: a meta-analysis of 23 trials. Asian J Surg. 2008;31(3):104–14.

    Article  PubMed  Google Scholar 

  31. Seiler CM, Bruckner T, Diener MK, Papyan A, Golcher H, Seidlmayer C, et al. Interrupted or continuous slowly absorbable sutures for closure of primary elective midline abdominal incisions: a multicenter randomized trial (INSECT: ISRCTN24023541). Ann Surg. 2009;249(4):576–82.

    Article  PubMed  Google Scholar 

  32. Diener MK, Voss S, Jensen K, Buchler MW, Seiler CM. Elective midline laparotomy closure: the INLINE systematic review and meta-analysis. Ann Surg. 2010;251(5):843–56.

    Article  PubMed  Google Scholar 

  33. Hoer J, Stumpf M, Rosch R, Klinge U, Schumpelick V. Prevention of incisional hernia. Chirurg. 2002;73(9):881–7.

    Article  CAS  PubMed  Google Scholar 

  34. Millbourn D, Cengiz Y, Israelsson LA. Effect of stitch length on wound complications after closure of midline incisions: a randomized controlled trial. Arch Surg. 2009;144(11):1056–9.

    Article  PubMed  Google Scholar 

  35. Israelsson LA, Jonsson T. Suture length to wound length ratio and healing of midline laparotomy incisions. Br J Surg. 1993;80(10):1284–6.

    Article  CAS  PubMed  Google Scholar 

  36. van Ramshorst GH, Klop B, Hop WC, Israelsson LA, Lange JF. Closure of midline laparotomies by means of small stitches: practical aspects of a new technique. Surg Technol Int. 2013;23:34–8.

    PubMed  Google Scholar 

  37. Cengiz Y, Blomquist P, Israelsson LA. Small tissue bites and wound strength: an experimental study. Arch Surg. 2001;136(3):272–5.

    Article  CAS  PubMed  Google Scholar 

  38. Deerenberg EB, Harlaar JJ, Steyerberg EW, Lont HE, Van Doorn HC, Heisterkamp J, Wijnhoven BP, Schouten WR, Cense HA, Stockmann HB, Berends FJ, Dijkhuizen FP, Dwarkasing RS, Jairam AP, van Ramshorst GH, Kleinrensink GJ, Jeekel J, Lange JF. Small bites versus large bites for closure of abdominal midline incisions (STITCH): a double-blind, multicentre, randomised controlled trial. Lancet. 2015;386:1254–60.

    Article  PubMed  Google Scholar 

  39. Millbourn D, Wimo A, Israelsson LA. Cost analysis of the use of small stitches when closing midline abdominal incisions. Hernia. 2013;18(6):775–80.

    Article  PubMed  Google Scholar 

  40. Muysoms FE, Antoniou SA, Bury K, Campanelli G, Conze J, Cuccurullo D, et al. European Hernia Society guidelines on the closure of abdominal wall incisions. Hernia. 2015;19(1):1–24.

    Article  CAS  PubMed  Google Scholar 

  41. Bouvier A, Rat P, Drissi-Chbihi F, Bonnetain F, Lacaine F, Mariette C, et al. Abdominal binders after laparotomy: review of the literature and French survey of policies. Hernia. 2014;18(4):501–6.

    Article  CAS  PubMed  Google Scholar 

  42. van Ramshorst GH, Eker HH, van der Voet JA, Jeekel J, Lange JF. Long-term outcome study in patients with abdominal wound dehiscence: a comparative study on quality of life, body image, and incisional hernia. J Gastrointest Surg. 2013;17(8):1477–84.

    Article  PubMed  Google Scholar 

  43. Christoffersen MW, Olsen BH, Rosenberg J, Bisgaard T. Randomized Clinical Trial on the postoperative use of an abdominal binder after laparoscopic umbilical and epigastric hernia repair. Hernia. 2014;19(1):147–53.

    Article  PubMed  Google Scholar 

  44. Nachiappan S, Markar S, Karthikesalingam A, Ziprin P, Faiz O. Prophylactic mesh placement in high-risk patients undergoing elective laparotomy: a systematic review. World J Surg. 2013;37(8):1861–71.

    Article  PubMed  Google Scholar 

  45. Strzelczyk J, Czupryniak L. Polypropylene mesh in prevention of postoperative hernia in bariatric surgery. Ann Surg. 2005;241(1):196. author reply-7.

    PubMed  PubMed Central  Google Scholar 

  46. Bhangu A, Fitzgerald JE, Singh P, Battersby N, Marriott P, Pinkney T. Systematic review and meta-analysis of prophylactic mesh placement for prevention of incisional hernia following midline laparotomy. Hernia. 2013;17(4):445–55.

    Article  CAS  PubMed  Google Scholar 

  47. Timmermans L, de Goede B, Eker HH, van Kempen BJ, Jeekel J, Lange JF. Meta-analysis of primary mesh augmentation as prophylactic measure to prevent incisional hernia. Dig Surg. 2013;30(4–6):401–9.

    Article  PubMed  Google Scholar 

  48. Paye F, Rongere C, Gendreau D, Lenriot JP. Intraperitoneal resorbable mesh in the prevention of postoperative wound dehiscence. A comparative study. Ann Chir. 1992;46(6):518–22.

    CAS  PubMed  Google Scholar 

  49. Gainant A, Boudinet F, Cubertafond P. Prevention of postoperative wound dehiscence in high risk patients. A randomized comparison of internally applied resorbable polyglactin 910 mesh and externally applied polyamide fiber mesh. Int Surg. 1989;74(1):55–7.

    CAS  PubMed  Google Scholar 

  50. Tohme C, Brechet E, Bernard A, Arnaud R, Viard H. Prevention of postoperative wound dehiscence. Comparative study of polyglactin 910 mesh and total reinforced extraperitoneal sutures. Ann Chir. 1991;45(6):513–6.

    CAS  PubMed  Google Scholar 

  51. Webster C, Neumayer L, Smout R, Horn S, Daley J, Henderson W, et al. Prognostic models of abdominal wound dehiscence after laparotomy. J Surg Res. 2003;109(2):130–7.

    Article  PubMed  Google Scholar 

  52. Gomez Diaz CJ, Rebasa Cladera P, Navarro Soto S, Hidalgo Rosas JM, Luna Aufroy A, Montmany Vioque S, et al. Validation of abdominal wound dehiscence’s risk model. Cir Esp. 2014;92(2):114–9.

    Article  PubMed  Google Scholar 

  53. van Ramshorst GH, Nieuwenhuizen J, Hop WC, Arends P, Boom J, Jeekel J, et al. Abdominal wound dehiscence in adults: development and validation of a risk model. World J Surg. 2010;34(1):20–7.

    Article  PubMed  Google Scholar 

  54. Kenig J, Richter P, Lasek A, Zbierska K, Zurawska S. The efficacy of risk scores for predicting abdominal wound dehiscence: a case-controlled validation study. BMC Surg. 2014;14:65.

    Article  PubMed  PubMed Central  Google Scholar 

  55. Junge K, Klinge U, Rosch R, Mertens PR, Kirch J, Klosterhalfen B, et al. Decreased collagen type I/III ratio in patients with recurring hernia after implantation of alloplastic prostheses. Langenbecks Arch Surg. 2004;389(1):17–22.

    Article  PubMed  Google Scholar 

  56. Klinge U, Si ZY, Zheng H, Schumpelick V, Bhardwaj RS, Klosterhalfen B. Abnormal collagen I to III distribution in the skin of patients with incisional hernia. Eur Surg Res. 2000;32(1):43–8.

    Article  CAS  PubMed  Google Scholar 

  57. Peeters E, De Hertogh G, Junge K, Klinge U, Miserez M. Skin as marker for collagen type I/III ratio in abdominal wall fascia. Hernia. 2014;18(4):519–25.

    Article  CAS  PubMed  Google Scholar 

  58. Rosch R, Junge K, Knops M, Lynen P, Klinge U, Schumpelick V. Analysis of collagen-interacting proteins in patients with incisional hernias. Langenbecks Arch Surg. 2003;387(11–12):427–32.

    CAS  PubMed  Google Scholar 

  59. van Ramshorst GH, Eker HH, Hop WC, Jeekel J, Lange JF. Impact of incisional hernia on health-related quality of life and body image: a prospective cohort study. Am J Surg. 2012;204(2):144–50.

    Article  PubMed  Google Scholar 

  60. Helgstrand F, Rosenberg J, Kehlet H, Bisgaard T. Outcomes after emergency versus elective ventral hernia repair: a prospective nationwide study. World J Surg. 2013;37(10):2273–9.

    Article  PubMed  Google Scholar 

  61. Martinez-Serrano MA, Pereira JA, Sancho JJ, Lopez-Cano M, Bombuy E, Hidalgo J, et al. Risk of death after emergency repair of abdominal wall hernias. Still waiting for improvement. Langenbecks Arch Surg. 2010;395(5):551–6.

    Article  PubMed  Google Scholar 

  62. Halasz NA. Dehiscence of laparotomy wounds. Am J Surg. 1968;116(2):210–4.

    Article  CAS  PubMed  Google Scholar 

  63. Keill RH, Keitzer WF, Nichols WK, Henzel J, DeWeese MS. Abdominal wound dehiscence. Arch Surg. 1973;106(4):573–7.

    Article  CAS  PubMed  Google Scholar 

  64. Waldhausen JH, Davies L. Pediatric postoperative abdominal wound dehiscence: transverse versus vertical incisions. J Am Coll Surg. 2000;190(6):688–91.

    Article  CAS  PubMed  Google Scholar 

  65. Campbell DP, Swenson O. Wound dehiscence in infants and children. J Pediatr Surg. 1972;7(2):123–6.

    Article  CAS  PubMed  Google Scholar 

  66. van Ramshorst GH, Salu NE, Bax NM, Hop WC, van Heurn E, Aronson DC, et al. Risk factors for abdominal wound dehiscence in children: a case-control study. World J Surg. 2009;33(7):1509–13.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Albertsmeier M, Seiler CM, Fischer L, Baumann P, Husing J, Seidlmayer C, et al. Evaluation of the safety and efficacy of MonoMax(R) suture material for abdominal wall closure after primary midline laparotomy-a controlled prospective multicentre trial: ISSAAC [NCT005725079]. Langenbecks Arch Surg. 2012;397(3):363–71.

    Article  PubMed  Google Scholar 

  68. Penninckx FM, Poelmans SV, Kerremans RP, Beckers JP. Abdominal wound dehiscence in gastroenterological surgery. Ann Surg. 1979;189(3):345–52.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  69. Khorgami Z, Shoar S, Laghaie B, Aminian A, Hosseini Araghi N, Soroush A. Prophylactic retention sutures in midline laparotomy in high-risk patients for wound dehiscence: a randomized controlled trial. J Surg Res. 2013;180(2):238–43.

    Article  PubMed  Google Scholar 

  70. Israelsson LA, Millbourn D. Closing midline abdominal incisions. Langenbecks Arch Surg. 2012;397(8):1201–7.

    Article  PubMed  Google Scholar 

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Correspondence to Gabrielle H. van Ramshorst M.D., Ph.D. .

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Jairam, A., van Ramshorst, G.H., Lange, J.F. (2016). Wound Closure and Postoperative Hernia Prevention Strategies. In: Novitsky, Y. (eds) Hernia Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-27470-6_5

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