Abstract
Clinical oncology is a specialty that currently holds a central role in the management of skin cancer patients, with rising importance in a broad range of settings not limited to metastatic disease, as in the past. Recent advances in the vast therapeutic arsenal comprising cytotoxic agents, small kinase inhibitors, monoclonal antibodies, and immunotherapy have drastically changed the natural of history of several hard-to-treat conditions, adding more complexity to the multidisciplinary approach of skin malignancies. A basic knowledge of the most frequently employed systemic agents is certainly useful to healthcare professionals interested in improving quality of care. The purpose of this chapter is to provide a brief overview of historical background, rationale, and toxicities of some of the most important categories of drugs employed in clinical oncology.
Beatriz Mendes Awni and Marcello Moro Queiroz are co-first authors.
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Awni, B.M., Queiroz, M.M., dos Santos Fernandes, G., Ribeiro, M.F.S.A. (2023). Principles of Clinical Oncology and Systemic Treatments. In: Abdalla, C.M.Z., Sanches, J.A., Munhoz, R.R., Belfort, F.A. (eds) Oncodermatology. Springer, Cham. https://doi.org/10.1007/978-3-031-29277-4_11
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