Abstract
The rise and spread of antimicrobial resistance among microbes represents one of today’s most pressing global health issues. To combat the antimicrobial resistance of pathogens, the ongoing development of novel antibiotics is still the primary approach. However, due to the stalled antibiotic development pipeline, it is vital that novel, practical, and accessible methods, distinct from antibiotics, will be established to combat antimicrobial-resistant pathogens.
One promising strategy is the medical application of natural products exhibiting antimicrobial properties. Traditionally, many types of natural products were applied to the treatment of a variety of diseases or medical conditions as natural remedies. In particular, components—directly or indirectly derived from plants—have attracted interest among researchers and clinicians due to their antimicrobial and antibiofilm properties, good safety profiles, and less likelihood of resistance development.
In this section, we discuss natural products with potential clinical applications against biofilm-related infections, such as honey, essential oils, and teas. We present current research based on animal models and clinical research, as well as in vitro studies.
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Acknowledgement
The author is thankful to Dr. Koh Nakamura and Yuki Suzuki for providing the photos of Sasa senanensis Rehder, and Manuka honey and tea. The author is also grateful to Ayaka Kubota, Yuka Masuta, Shizuka Sugawara, and Yumiko Kimura for their help in preparing the manuscript. The authors declare that the chapter was written in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. This review was supported by JSPS KAKENHI Grant Number 17H06491, 18 K16871, and 18KK0444 for MS
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Suzuki, M. (2022). Learning from Nature: Naturally Derived Remedies. In: Richter, K., Kragh, K.N. (eds) Antibiofilm Strategies. Springer Series on Biofilms, vol 11. Springer, Cham. https://doi.org/10.1007/978-3-031-10992-8_13
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