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Source Control in Intra-Abdominal Infections

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Infections in Surgery

Part of the book series: Hot Topics in Acute Care Surgery and Trauma ((HTACST))

Abstract

Intra-abdominal infections are a common cause of an acute abdomen worldwide, which are frequently associated with significant morbidity and high mortality. Patients with peritonitis secondary to an intra-abdominal infection require prompt diagnosis followed by aggressive and timely intervention. Source control, in combination with antibiotic therapy, are the two pillars of care for patients with intra-abdominal infections. In such cases, the surgeon must employ resuscitative measures in preparation for the source control procedure. Techniques for obtaining source control vary widely depending on the site of infection, acuity of infection, and physiologic state of the host. Targeted antibiotic therapy is an important adjunct after source control has been achieved in complicated infections. In this chapter, we discuss the underlying physiology related to intra-abdominal infections and the essential management concepts necessary to obtain source control.

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Authors and Affiliations

  1. Division of General Surgery, School of Medicine, Stanford University, Stanford, CA, USA

    Joshua D. Jaramillo, Joseph D. Forrester & David A. Spain

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  1. Joshua D. Jaramillo
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  2. Joseph D. Forrester
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  3. David A. Spain
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Correspondence to David A. Spain .

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Editors and Affiliations

  1. Department of Surgery, Macerata Hospital, Macerata, Italy

    Massimo Sartelli

  2. Comparative Effectiveness and Clinical Outcomes Research Center - CECORC, Riverside University Health System Medical Center, Moreno Valley, CA, USA

    Raul Coimbra

  3. Department of infectious diseases, Ospedale di Bolzano, Bolzano, Italy

    Leonardo Pagani

  4. Department of Surgery, Anadolu Medical Centre, Kocaeli, Turkey

    Kemal Rasa

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Jaramillo, J.D., Forrester, J.D., Spain, D.A. (2021). Source Control in Intra-Abdominal Infections. In: Sartelli, M., Coimbra, R., Pagani, L., Rasa, K. (eds) Infections in Surgery. Hot Topics in Acute Care Surgery and Trauma. Springer, Cham. https://doi.org/10.1007/978-3-030-62116-2_11

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