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Bioactives for Neuronal and Immune Functions

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Food Bioactives and Health

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Abstract

The positive effects of certain dietary nutrients and phytochemicals on human health include the prevention of a non-communicable diseases (NCD) as well as the enhancement of the healing processes by decreasing the time needed for healing and improving the outcomes. A diet that is low in saturated fats and carbohydrates and that is high in fiber, antioxidants such as polyphenols and monounsaturated and omega-3 fatty acids, phytosterols and probiotics are known as a healthy diet. It has been shown that polyphenols are interfering with immune cells regulation, gene expression and pro-inflammatory cytokines’ synthesis. As such, these molecules are associated with extended health benefits, playing an important role in the prevention and treatment of various chronic conditions, such as neurological disorders. Omega-3 fatty acids are known for their positive health effects through their anti-inflammatory properties as well as their impact on gut microbiota. DHA and EPA are known for being essential in neuronal/brain functioning and its immunomodulatory properties. Intestinal immune stress associated with low omega-3 availability might be also involved in the development of neuro-inflammation and progression of related diseases. Further studies are needed in order to understand the real impact and benefits of omega-3 fatty acids on the development of non-communicable diseases (NCD) including neurological conditions that are developed as a consequence of neuro-inflammation.

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Acknowledgment

This transnational project is part of the ERA-Net SUSFOOD2—project no145. SUSPUFA, with funding provided by national/ regional sources and co-funding by the European Union´s Horizon 2020 research and innovation programme and by Innovation fund of Republic of Serbia—project no. 50138.

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  1. Faculty of Sciences, University of Novi Sad, Novi Sad, Serbia

    Mimica-Dukić Neda & Ivana Beara

  2. Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia

    Tamara Vojnović &  Cvejić Jelena Helene

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  1. Mimica-Dukić Neda
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  1. Galanakis Laboratories, Chania, Greece

    Charis M. Galanakis

  2. Food Waste Recovery Group, Vienna, Austria

    Charis M. Galanakis

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Mimica-Dukić Neda, Beara, I., Vojnović, T., Cvejić Jelena Helene (2021). Bioactives for Neuronal and Immune Functions. In: Galanakis, C.M. (eds) Food Bioactives and Health. Springer, Cham. https://doi.org/10.1007/978-3-030-57469-7_8

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