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When the Race Is Lost: The Clinical Impact of Prosthetic Joint Infections

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Racing for the Surface

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Abstract

Joint arthroplasty, a procedure that can relieve patients of life-altering and debilitating pain, has proven to be so successful that over 1,000,000 procedures are performed annually in the USA alone. However, a prosthetic joint infection represents a devastating complication for patients which can lead to not only revision surgery but possible permanent loss of function, amputation, and even death. Infection can present not only in the immediate postoperative period but at any point for the duration of the implant’s life.

The challenges confronting providers are numerous. Diagnostic testing has varying sensitivities and specificities depending on duration of infection meaning there is no true “gold standard” for testing. Additionally, once the diagnosis of infection is made, treatment options are limited and have high rates of morbidity and mortality.

Given the impending rise in total joint arthroplasty case volume and subsequent revision case volume due to PJI, an urgent need exists for continued work in the development of preventive, diagnostic, and therapeutic tools.

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Acknowledgements

The authors would like to thank Suzanne Danley for her assistance and critical review of the manuscript.

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Authors and Affiliations

  1. Department of Orthopaedics, West Virginia University, Morgantown, WV, USA

    Justin Vaida & Matthew J. Dietz

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  1. Justin Vaida
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  2. Matthew J. Dietz
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Correspondence to Justin Vaida .

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Editors and Affiliations

  1. Department of Orthopaedics, West Virginia University, Morgantown, WV, USA

    Bingyun Li

  2. Microbiology Lab, AO Research Institute Davos, Davos Platz, Graubünden, Switzerland

    Thomas Fintan Moriarty

  3. Department of Chemical Engineering, Northeastern University, Boston, MA, USA

    Thomas Webster

  4. Engineering and Medicine, University of Manitoba, Winnipeg, MB, Canada

    Malcolm Xing

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Vaida, J., Dietz, M.J. (2020). When the Race Is Lost: The Clinical Impact of Prosthetic Joint Infections. In: Li, B., Moriarty, T., Webster, T., Xing, M. (eds) Racing for the Surface. Springer, Cham. https://doi.org/10.1007/978-3-030-34475-7_1

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