Continuing the Investigation

Viruses and Neurological Disorders
  • Steven Specter
  • Mauro Bendinelli
  • Herman Friedman
Part of the Infectious Agents and Pathogenesis book series (IAPA)


Numerous questions are left unanswered in this volume and provide most intriguing areas for further investigations. In spite of considerable progress, knowledge is far from satisfactory even in the field of acute neurological diseases for which a definite direct etiology is well established. For some of these diseases, Japanese encephalitis for example, we are in great need of efficient vaccines.1 In addition, for such diseases it is especially urgent to develop better diagnostic procedures, since in even the most modern diagnostic virology facilities the etiologic agent remains unrecognized in over 30% of presumed cases of acute viral meningitis and in over 80% of presumed cases of acute viral encephalitis. Indeed, the precise etiologic diagnosis of viral infection of the nervous system (NS) in general is still fraught with difficulties. For example, the association of cerebral malformations and other neurological birth defects with antecedent viral infection of the mother is often beyond present methodologies.


Human Immunodeficiency Virus Japanese Encephalitis Rubella Virus Viral Etiology Japanese Encephalitis Vaccine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1992

Authors and Affiliations

  • Steven Specter
    • 1
  • Mauro Bendinelli
    • 2
  • Herman Friedman
    • 1
  1. 1.Department of Microbiology and ImmunologyUniversity of South Florida, College of MedicineTampaUSA
  2. 2.Department of BiomedicineUniversity of PisaPisaItaly

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