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Neuropathogenic Viruses and Immunity

  • Book
  • © 1992

Overview

Editors:
  1. Steven Specter

    1. Department of Microbiology and Immunology, University of South Florida, College of Medicine, Tampa, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Mauro Bendinelli

    1. Department of Biomedicine, University of Pisa, Pisa, Italy

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    You can also search for this editor in PubMed   Google Scholar

  3. Herman Friedman

    1. Department of Microbiology and Immunology, University of South Florida, College of Medicine, Tampa, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Infectious Agents and Pathogenesis (IAPA)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xix
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  2. Viruses and Neuropsychiatric Disorders

    1. Viruses and Neuropsychiatric Disorders

      • Steven Specter, Mauro Bendinelli, Herman Friedman
      Pages 1-12

  3. General Information

    1. Front Matter

      Pages 13-13
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    2. Immune Responses and the Central Nervous System

      • William R. Tyor, Richard T. Johnson
      Pages 15-39

    3. Virus Infection of Peripheral Nerve

      • Michael C. Graves, Harry V. Vinters
      Pages 41-60

  4. Animal Models

    1. Front Matter

      Pages 61-61
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    2. Visna, a Lentiviral Disease of Sheep

      • Gudmundur Pétursson, Ólafur S. Andrésson, Gudmundur Georgsson
      Pages 63-78

    3. Theiler’s Virus-Induced Demyelinating Disease in Mice

      • Howard L. Lipton, Mauro C. dal Canto
      Pages 79-91

    4. Neurotropic Retroviruses of Mice, Cats, Macaques, and Humans

      • Murray Gardner, Andrew Lackner, Linda Lowenstine
      Pages 93-109

    5. Scrapie

      • Richard I. Carp
      Pages 111-136

  5. Human Infections of the CNS

    1. Front Matter

      Pages 137-137
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    2. Enteroviruses

      • Joseph L. Melnick
      Pages 139-153

    3. Pathogenesis and Immunology of Herpesvirus Infections of the Nervous System

      • Anthony A. Nash, J. Matthias Löhr
      Pages 155-175

    4. Paramyxoviruses

      • Claes Örvell
      Pages 177-205

    5. Human Papovaviruses

      • Eugene O. Major, Dominick A. Vacante, Sidney A. Houff
      Pages 207-227

    6. Neurological Aspects of Human Immunodeficiency Virus Infection

      • Howard E. Gendelman, Seymour Gendelman
      Pages 229-254

    7. Alphaviruses, Flaviviruses, and Bunyaviruses

      • Diane E. Griffin
      Pages 255-274

  6. Perspectives

    1. Front Matter

      Pages 275-275
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    2. Antiglycolipid Immunity

      • H. E. Webb
      Pages 277-302

    3. Viruses and Schizophrenia

      • Janice R. Stevens, Lesley M. Hallick
      Pages 303-316
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Keywords

About this book

There has been a tremendous increase in interest in the neuropathogenicity of viruses during the past decade as we have come to recognize that the human immunodeficiency virus, which causes the acquired immunodeficiency syndrome (AIDS), can infect glial cells and cause neurological disease. Yet this increase has not been limited to AIDS but has extended to viruses that infect either or both the central and peripheral nervous systems. The changes examined here include both neurological and psychological diseases or syndromes. Moreover, the chapters in this volume review the interaction of the host immune system with the viruses examined and how such interactions may increase or decrease the neuropatho­ genicity of the viruses. Questions regarding viral neuropathogenesis include: (I) What is the mode of transmission of virus to the nervous system? (2) What types of cells are infected, and do they contain receptors for the virus? (3) What is the extent of damage that results from viral infection? (4) What are the immunologic mecha­ nisms by which damage is mediated or limited? Many of these questions remain unanswered, but this volume delves into efforts to provide some answers.

Editors and Affiliations

  • Department of Microbiology and Immunology, University of South Florida, College of Medicine, Tampa, USA

    Steven Specter, Herman Friedman

  • Department of Biomedicine, University of Pisa, Pisa, Italy

    Mauro Bendinelli

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