Abstract
F plasmid of Escherichia coli is known to be stably maintained in dividing cells, despite of low copy number per cell. Mini-F plasmids, which were constructed in vitro from the 9.2 kb EcoRI-generated f5 fragment of the F plasmid, are also stably inherited, even though the copy number is still low (for review, see Ref. 1). We have sought to understand the molecular mechanisms involved in the stable maintenance of mini-F.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Lane, H.E.D. (1981) Replication and incompatibility of F and plasmids in the incFI group. Plasmid 5: 100–126.
Ogura, T., and S. Hiraga (1983a) Partition mechanism of F plasmid: Two plasmid gene-encoded products and a cis-acting region are involved in partition. Cell 32: 351–360.
Ogura, T., and S. Hiraga (1983b) Mini-F plasmid genes that couple host cell division to plasmid proliferation. Proc. Natl. Acad. Sci., USA 80: 4784–4788.
Murotsu, T., K. Matsubara, H. Sugisaki, and M. Takanami (1981) Nine unique repeating sequences in a region essential for replication and incompatibility of the mini-F plasmid. Gene 15: 257–271.
Watson, L.A., S.H. Phua, P.L. Bergquist, and H.E.D. Lane (1982) An Mr 29,000 protein is essential for mini-F maintenance in E. coli. Gene 19: 173–178.
Maki, S., M. Kuribayashi, T. Miki, and T. Horiuchi (1983) An amber replication mutant of F plasmid mapped in the minimal replication region. Mol. Gen. Genet. 191: 231–237.
Kline, B.C., and J. Trawick (1983) Identification and characterization of a second copy number control gene in mini-F plasmids. Mol. Gen. Genet. 192: 408–415.
Gardner, R.C., L. Malcolm, P.L. Bergquist, and H.E.D. Lane (1982) IncD, a genetic locus in F responsible for incompatibility with several plasmids of the incFI group. Mol. Gen. Genet. 188: 345–352.
Tolun, A., and D.R. Helinski (1981) Direct repeats of the F plasmid incC region express F incompatibility. Cell 24: 687–694.
Komai., N., T. Nishizawa, Y. Hayakawa, T. Murotsu, and K. Matsubara (1982) Detection and mapping of six mini-F-encoded proteins by cloning analysis of dissected mini-F segments. Mol. Gen. Genet. 186: 193–203.
Tsutsui, H., A. Fujiyama, T. Murotsu, and K. Matsubara (1983) Role of nine repeating sequences of the mini-F genome for expression of F-specific incompatibility phenotype and copy number control. J. Bact. 155:337–344.
Hiraga, S. (1976) Novel F prime factors able to replicate in Escherichia coli Hfr strains. Proc. Natl. Acad. Sci., USA 73: 198–202.
Joh, K., and S. Hiraga (1979) Genetic mapping of the chromosomal replication origin of Salmonella typhimurium. J. Bact. 138: 297–304.
Miki, T., S. Hiraga, T. Nagata, and T. Yura (1978) Bacteriophage λ carrying the Escherichia coli chromosomal region of the replication origin. Proc. Natl. Acad. Sci., USA 75:5099–5103.
Ogura, T., T. Miki, and S. Hiraga (1980) Copy-number mutants of the plasmid carrying the replication origin of the Escherichia coli chromosome: Evidence for a control region of replication. Proc. Natl. Acad. Sci., USA 77: 3993–3997.
Austin, S., and A. Wierzbicki (1983) Two mini-F-encoded proteins are essential for equipartition. Plasmid 10: 73–81.
Phua, S.H., P.L. Bergquist, and H.E.D. Lane (1982) Effects of Tn5 insertion in the incD region on mini-F maintenance and polypeptide synthesis. Mol. Gen. Genet. 188: 353–355.
Nordström, K., S. Molin, and H. Aagaard-Hansen (1980) Partitioning of plasmid R1 in Escherichia coli. II. Incompatibility properties of the partitioning system. Plasmid 4: 332–349.
Austin, S., and A. Abeles (1983) Partition of unit-copy miniplasmids to daughter cells. J. Mol. Biol. 169: 373–387.
Mori, H., T. Ogura, and S. Hiraga (1984) Prophage induction caused by mini-F plasmid genes. Mol. Gen. Genet. (in press).
Bex, F., H. Karoui, L. Rokeach, P. Drèze, L. Garcia, and M. Couturier (1983) Mini-F encoded proteins: Identification of a new 10.5 kilodalton species. EMBO J. 2: 1853–1861.
Karoui, H., F. Bex, P. Drèze, and M. Couturier (1983) Ham22, a mini-F mutation which is lethal to host cell and promotes recA-dependent induction of lambdoid prophage. EMBO J. 2:1863–1868.
Miki, T., K. Yoshioka, and T. Horiuchi (1984) Control of cell division by sex factor F in Escherichia coli. I. The 42.84-43.6 F segment couples cell division of the host bacteria with replication of plasmid DNA. J. Mol. Biol. 174 (in press).
Miki, T., Z.T. Chang, and T. Horiuchi (1984) Control of cell division by sex factor F in Escherichia coli. II. Identification of genes for inhibitor protein and trigger protein on the 42.84-43.6 F segment J. Mol. Biol 174 (in press).
D’Ari, R., and 0. Huisman (1983) Novel mechanism of cell division inhibition associated with the SOS response in Escherichia coli. J. Bact. 156: 243–250.
Borek, E., and A. Ryan (1960) The transfer of a biologically active irradiation product from cell to cell. Biochim. Biophys. Acta 41: 67–73.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Plenum Press, New York
About this chapter
Cite this chapter
Hiraga, S., Ogura, T., Mori, H., Tanaka, M. (1985). Mechanisms Essential for Stable Inheritance of Mini-F Plasmid. In: Helinski, D.R., Cohen, S.N., Clewell, D.B., Jackson, D.A., Hollaender, A. (eds) Plasmids in Bacteria. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2447-8_34
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2447-8_34
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9487-0
Online ISBN: 978-1-4613-2447-8
eBook Packages: Springer Book Archive