Abstract
Esophageal carcinoma is an aggressive disease with early lymphatic and hematogenous dissemination. The incidence of esophageal carcinoma has been rising steadily over the past decades due to the increasing number of patients with distal esophageal and gastroesophageal junction adenocarcinoma. Despite a reduced risk of esophagectomy due to centralization of surgery, the use of neoadjuvant treatments, advances in surgical techniques, and improvements in perioperative care, esophageal surgery is still associated with substantial morbidity. This chapter will discuss the incidence, diagnosis, and treatment of the most important nonsurgical and surgical complications associated with surgical resection of the esophagus. In addition, minimally invasive esophageal surgery will be discussed followed by esophageal surgery for benign disease.
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References
Pohl H, Welch HG. The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst. 2005;97(2):142–6.
Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol. 2006;24(14):2137–50.
Hulscher JB, van Sandick JW, Tijssen JG, Obertop H, van Lanschot JJ. The recurrence pattern of esophageal carcinoma after transhiatal resection. J Am Coll Surg. 2000;191(2):143–8.
Mariette C, Balon JM, Piessen G, Fabre S, Van Seuningen I, Triboulet JP. Pattern of recurrence following complete resection of esophageal carcinoma and factors predictive of recurrent disease. Cancer. 2003;97(7):1616–23.
Hulscher JB, van Sandick JW, de Boer AG, Wijnhoven BP, Tijssen JG, Fockens P, et al. Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus. N Engl J Med. 2002;347(21):1662–9.
Omloo JM, Lagarde SM, Hulscher JB, Reitsma JB, Fockens P, van Dekken DH, et al. Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the mid/distal esophagus: five-year survival of a randomized clinical trial. Ann Surg. 2007;246(6):992–1000.
Wu PC, Posner MC. The role of surgery in the management of oesophageal cancer. Lancet Oncol. 2003;4(8):481–8.
Swisher SG, Deford L, Merriman KW, Walsh GL, Smythe R, Vaporicyan A, et al. Effect of operative volume on morbidity, mortality, and hospital use after esophagectomy for cancer. J Thorac Cardiovasc Surg. 2000;119(6):1126–32.
Wouters MW, Wijnhoven BP, Karim-Kos HE, Blaauwgeers HG, Stassen LP, Steup WH, et al. High-volume versus low-volume for esophageal resections for cancer: the essential role of case-mix adjustments based on clinical data. Ann Surg Oncol. 2008;15(1):80–7.
van Heijl M, van Lanschot JJ, Blom RL, Bergman JJ, Ten Kate FJ, Busch OR, et al. Outcomes of 16 years of oesophageal surgery: low postoperative mortality and improved long-term survival. Ned Tijdschr Geneeskd. 2010;154:A1156.
Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205–13.
Lagarde SM, Reitsma JB, Maris AK, van Berge Henegouwen MI, Busch OR, Obertop H, et al. Preoperative prediction of the occurrence and severity of complications after esophagectomy for cancer with use of a nomogram. Ann Thorac Surg. 2008;85(6):1938–45.
Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, et al. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med. 1994;149(3 Pt 1):818–24.
Zingg U, Smithers BM, Gotley DC, Smith G, Aly A, Clough A, et al. Factors associated with postoperative pulmonary morbidity after esophagectomy for cancer. Ann Surg Oncol. 2011;18(5):1460–8.
Schoppmann SF, Prager G, Langer FB, Riegler FM, Kabon B, Fleischmann E, et al. Open versus minimally invasive esophagectomy: a single-center case controlled study. Surg Endosc. 2010;24(12):3044–53.
Zingg U, McQuinn A, DiValentino D, Esterman AJ, Bessell JR, Thompson SK, et al. Minimally invasive versus open esophagectomy for patients with esophageal cancer. Ann Thorac Surg. 2009;87(3):911–9.
Tisdale JE, Wroblewski HA, Wall DS, Rieger KM, Hammoud ZT, Young JV, et al. A randomized, controlled study of amiodarone for prevention of atrial fibrillation after transthoracic esophagectomy. J Thorac Cardiovasc Surg. 2010;140(1):45–51.
Malhotra SK, Kaur RP, Gupta NM, Grover A, Ramprabu K, Nakra D. Incidence and types of arrhythmias after mediastinal manipulation during transhiatal esophagectomy. Ann Thorac Surg. 2006;82(1):298–302.
Nattel S. New ideas about atrial fibrillation 50 years on. Nature. 2002;415(6868):219–26.
Murthy SC, Law S, Whooley BP, Alexandrou A, Chu KM, Wong J. Atrial fibrillation after esophagectomy is a marker for postoperative morbidity and mortality. J Thorac Cardiovasc Surg. 2003;126(4):1162–7.
Walther B, Johansson J, Johnsson F, Von Holstein CS, Zilling T. Cervical or thoracic anastomosis after esophageal resection and gastric tube reconstruction: a prospective randomized trial comparing sutured neck anastomosis with stapled intrathoracic anastomosis. Ann Surg. 2003;238(6):803–12.
Boone J, Livestro DP, Elias SG, Borel Rinkes IH, Van HR. International survey on esophageal cancer: part I surgical techniques. Dis Esophagus. 2009;22(3):195–202.
van Heijl M, van Wijngaarden AK, Lagarde SM, Busch OR, van Lanschot JJ, van Berge Henegouwen MI. Intrathoracic manifestations of cervical anastomotic leaks after transhiatal and transthoracic oesophagectomy. Br J Surg. 2010;97(5):726–31.
Urschel JD, Blewett CJ, Bennett WF, Miller JD, Young JE. Handsewn or stapled esophagogastric anastomoses after esophagectomy for cancer: meta-analysis of randomized controlled trials. Dis Esophagus. 2001;14(3–4):212–7.
Boone J, Rinkes IB, van Leeuwen M, van Hillegersberg R. Diagnostic value of routine aqueous contrast swallow examination after oesophagectomy for detecting leakage of the cervical oesophagogastric anastomosis. ANZ J Surg. 2008;78(9):784–90.
Low DE. Diagnosis and management of anastomotic leaks after esophagectomy. J Gastrointest Surg. 2011;15:1319–22.
Lagarde SM, Omloo JM, de Jong K, Busch OR, Obertop H, van Lanschot JJ. Incidence and management of chyle leakage after esophagectomy. Ann Thorac Surg. 2005;80(2):449–54.
Omloo JM, Lagarde SM, Vrouenraets BC, Busch OR, van Lanschot JJ. Compartimentalization for chylothorax originating from the abdomen after extended esophagectomy. Report of two cases and review of the literature. Dig Surg. 2006;23(1–2):86–92.
Gelpke H, Grieder F, Decurtins M, Cadosch D. Recurrent laryngeal nerve monitoring during esophagectomy and mediastinal lymph node dissection. World J Surg. 2010;34(10):2379–82.
Gockel I, Kneist W, Keilmann A, Junginger T. Recurrent laryngeal nerve paralysis (RLNP) following esophagectomy for carcinoma. Eur J Surg Oncol. 2005;31(3):277–81.
Bakhos C, Alazemi S, Michaud G, DeCamp MM. Staged repair of benign tracheo-neo-esophageal fistula 12 years after esophagectomy for esophageal cancer. Ann Thorac Surg. 2010;90(6):e83–5.
Buskens CJ, Hulscher JB, Fockens P, Obertop H, van Lanschot JJ. Benign tracheo-neo-esophageal fistulas after subtotal esophagectomy. Ann Thorac Surg. 2001;72(1):221–4.
van Heijl M, Gooszen JA, Fockens P, Busch OR, van Lanschot JJ, van Berge Henegouwen MI. Risk factors for development of benign cervical strictures after esophagectomy. Ann Surg. 2010;251(6):1064–9.
Nederlof N, Tilanus HW, Tran TC, Hop WC, Wijnhoven BP, de Jonge J. End-to-end versus end-to-side esophagogastrostomy after esophageal cancer resection: a prospective randomized study. Ann Surg. 2011.
Honkoop P, Siersema PD, Tilanus HW, Stassen LP, Hop WC, van Blankenstein M. Benign anastomotic strictures after transhiatal esophagectomy and cervical esophagogastrostomy: risk factors and management. J Thorac Cardiovasc Surg. 1996;111(6):1141–6.
van Hooft JE, van Berge Henegouwen MI, Rauws EA, Bergman JJ, Busch OR, Fockens P. Endoscopic treatment of benign anastomotic esophagogastric strictures with a biodegradable stent. Gastrointest Endosc. 2011;73(5):1043–7.
Pierie JP, de Graaf PW, Poen H, van der Tweel I, Obertop H. Incidence and management of benign anastomotic stricture after cervical oesophagogastrostomy. Br J Surg. 1993;80(4):471–4.
Biere SS, Cuesta MA, van der Peet DL. Minimally invasive versus open esophagectomy for cancer: a systematic review and meta-analysis. Minerva Chir. 2009;64:121–33.
Nagpal K, Ahmed K, Vats A, et al. Is minimally invasive surgery beneficial in the management of esophageal cancer ? A meta-analysis. Surg Endosc. 2010;24:1621–9.
Sgourakis G, Gockel I, Radtke A, et al. Minimally invasive versus open esophagectomy: meta-analysis of outcomes. Dig Dis Sci. 2010;55:3031–40.
Biere SS, van Berge Henegouwen MI, Maas KW, et al. Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial. Lancet. 2012;379:1887–92.
Locke III GR, Talley NJ, Fett SL, Zinsmeister AR, Melton III LJ. Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota. Gastroenterology. 1997 May;112(5):1448–56.
van Lanschot JJ, Gouma DJ, Jansen PLM, Jones EA, Pinedo HM, Schouten WR, et al. Integrated medical and surgical gastroenterology. Houten: Bohn Stafleu Van Loghum; 2004.
Boeckxstaens GE, Annese V, des Varannes SB, Chaussade S, Costantini M, Cuttitta A, et al. Pneumatic dilation versus laparoscopic Heller's myotomy for idiopathic achalasia. N Engl J Med. 2011;364(19):1807–16.
Draaisma WA, Gooszen HG, Tournoij E, Broeders IA. Controversies in paraesophageal hernia repair: a review of literature. Surg Endosc. 2005;19(10):1300–8.
Iqbal A, Haider M, Desai K, Garg N, Kavan J, Mittal S, et al. Technique and follow-up of minimally invasive Heller myotomy for achalasia. Surg Endosc. 2006;20(3):394–401.
Erdogan A, Gurses G, Keskin H, Demircan A. The sealing effect of a fibrin tissue patch on the esophageal perforation area in primary repair. World J Surg. 2007;31(11):2199–203.
Trus TL, Bax T, Richardson WS, Branum GD, Mauren SJ, Swanstrom LL, et al. Complications of laparoscopic paraesophageal hernia repair. J Gastrointest Surg. 1997;1(3):221–7.
Haider M, Iqbal A, Salinas V, Karu A, Mittal SK, Filipi CJ. Surgical repair of recurrent hiatal hernia. Hernia. 2006;10(1):13–9.
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Blom, R.L.G.M., van der Peet, D.L., van Berge Henegouwen, M.I. (2014). Prevention and Treatment of Major Complications After Esophageal Surgery. In: Cuesta, M., Bonjer, H. (eds) Treatment of Postoperative Complications After Digestive Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-4354-3_8
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DOI: https://doi.org/10.1007/978-1-4471-4354-3_8
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