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The Strategies of Nanomaterials for Therapy

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Nanomedicine in Brain Diseases

Abstract

Brain diseases, including brain tumor, Alzheimer’s and Parkinson’s diseases, and stroke, are becoming increasingly widespread in the aging population. However, due to our limited knowledge of the pathogenesis of these diseases and inefficient drug delivery system, the treatments for these disorders are still major challenges in modern medicine. Nanomaterials have recently emerged as an effective tool in biomedical fields, which have unique properties and structures conferring improved efficacy, safety, sensitivity, and the potential to be personalized. With these advantages, nanomaterial-based therapies are rapidly progressing and show promise to revolutionize the way we treat brain diseases. In this chapter, the state of the art of current nanomaterials in the treatment of brain diseases will be described, with discussions on the prospects and ongoing challenges that must be overcome.

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Acknowledgments

This work was supported by the National Key Research and Development Program of China (2016YFA0203600), the National Natural Science Foundation of China (31822019, 51703195, 91859116), One Belt and One Road International Cooperation Project from Key Research and Development Program of Zhejiang Province (2019C04024), the Zhejiang Provincial Natural Science Foundation of China (LGF19C100002), the Fundamental Research Funds for the Central Universities (2018QNA7020), and “Thousand Talents Program” for Distinguished Young Scholars.

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  1. Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China

    Yang Du, Shuying Wang, Fangyuan Li & Daishun Ling

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  1. Yang Du
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  2. Shuying Wang
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  3. Fangyuan Li
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Correspondence to Fangyuan Li or Daishun Ling .

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  1. State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, Tianjin, China

    Xue Xue

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Du, Y., Wang, S., Li, F., Ling, D. (2019). The Strategies of Nanomaterials for Therapy. In: Xue, X. (eds) Nanomedicine in Brain Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-13-8731-9_4

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