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Immunotechnological Advancements in Developing Vaccines for Lymphatic Filariasis

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Lymphatic Filariasis

Abstract

As we head toward the elimination of LF through mass drug administration (MDA) and vector control programs, it is equally reasonable to sustain efforts on vaccine development on a long-term basis. This prophylactic approach will give a foothold for complete protection in endemic areas from future emergence of infection and will also strengthen the current MDA efforts. Currently, we do not have any vaccines to combat multicellular infectious agents leaving alone the neglected infectious diseases like filariasis. But there have been significant efforts on the part of India toward extensive basic research in the identification and preclinical animal model validation of suitable vaccine candidates. This review gives a summary of these efforts that would be pivotal for future clinical vaccine studies in lymphatic filariasis (LF).

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  1. Centre for Biotechnology, Anna University, Chennai, India

    Prince R. Prabhu, Jayaprakasam Madhumathi & Perumal Kaliraj

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  1. Advisor, SpoRIC, VIT University, Vellore, Tamil Nadu, India

    Brij Kishore Tyagi

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Prabhu, P.R., Madhumathi, J., Kaliraj, P. (2018). Immunotechnological Advancements in Developing Vaccines for Lymphatic Filariasis. In: Tyagi, B. (eds) Lymphatic Filariasis. Springer, Singapore. https://doi.org/10.1007/978-981-13-1391-2_5

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