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Is There an Optimum System for Culturing Human Embryos?

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Emerging Topics in Reproduction

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Abstract

Processes within the IVF laboratory are critical in achieving high success rates from assisted reproduction. These various processes make up the “culture system,” and optimizing each of these variables is crucial. Importantly, within the context of the entire culture system, “optimal” conditions may vary slightly from laboratory to laboratory. However, initial gamete quality aside and accounting for laboratory-specific considerations, there are critical components of the culture system that are important to maximizing resulting embryo development. Items such as incubator type and management, strict monitoring, and control of environmental variables like use of low oxygen, temperature, pH, and osmolality are of paramount importance. Careful screening and use of culture media, protein, and oil are all required to avoid potentially harmful conditions for embryo development.

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Authors and Affiliations

  1. CCRM IVF Network, Lone Tree, CO, USA

    Jason E. Swain PhD, HCLD

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  1. Jason E. Swain PhD, HCLD
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Editors and Affiliations

  1. Division of Andrology, University of Utah School of Medicine, Salt Lake City, Utah, USA

    Douglas T. Carrell

  2. Department of Obstetrics and Gynecology, Brigham and Women’s Hospital, Boston, Massachusetts, USA

    Catherine Racowsky

  3. Department of Urology, Weill Cornell Medical College, New York, New York, USA

    Peter N. Schlegel

  4. NICHD, National Institutes of Health, Bethesda, Maryland, USA

    Alan H. DeCherney

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Swain, J.E. (2018). Is There an Optimum System for Culturing Human Embryos?. In: Carrell, D., Racowsky, C., Schlegel, P., DeCherney, A. (eds) Emerging Topics in Reproduction. Springer, Cham. https://doi.org/10.1007/978-3-319-90823-6_9

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