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Bone: Functions, Structure and Physiology

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The Computational Mechanics of Bone Tissue

Part of the book series: Lecture Notes in Computational Vision and Biomechanics ((LNCVB,volume 35))

Abstract

In this chapter, bone functions, regulation, morphological structure and physiology are revisited. Bone is a highly complex tissue, very sensitive and responsive to external and internal stimuli, and intimately intertwined with other organs. From embryogenesis to endocrine regulation and bone remodelling, a global assessment is presented. Considering the scope of this book, special emphasis is given to how cell structure and tissue organization modulate the response to mechanical stimuli.

Joana da Costa Reis and Maria Teresa Oliveira contributed equally to this work.

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Acknowledgements

This work has been partially supported by the European Commission under the 7th Framework Programme through the project Restoration, grant agreement CP-TP 280575-2 and through Portugal 2020/Alentejo 2020, grant POCI-01-0145-FEDER-032486. The support from Hamamatsu Photonics in providing the NanoZoomer SQ is also gratefully acknowledged. The authors would also like to thank Mr. Pedro Félix Pinto for the artwork included in this chapter that he so kindly prepared and made available.

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  1. Escola de Ciências e Tecnologia, Universidade de Évora, Largo dos Colegiais, Évora, Portugal

    Joana da Costa Reis & Maria Teresa Oliveira

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  1. Joana da Costa Reis
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  2. Maria Teresa Oliveira
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Correspondence to Joana da Costa Reis or Maria Teresa Oliveira .

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  1. Department of Mechanical Engineering, School of Engineering, Polytechnic of Porto (ISEP), Porto, Portugal

    Jorge Belinha

  2. Departament de Patologia i Terapèutica Experimental, University of Barcelona, Barcelona, Spain

    Maria-Cristina Manzanares-Céspedes

  3. Department of Mechanical Engineering, University of Aveiro, Aveiro, Portugal

    António M. G. Completo

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da Costa Reis, J., Oliveira, M.T. (2020). Bone: Functions, Structure and Physiology. In: Belinha, J., Manzanares-Céspedes, MC., Completo, A. (eds) The Computational Mechanics of Bone Tissue. Lecture Notes in Computational Vision and Biomechanics, vol 35. Springer, Cham. https://doi.org/10.1007/978-3-030-37541-6_1

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