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Helicobacter pylori

Basic Mechanisms to Clinical Cure

  • Book
  • © 1994

Overview

Editors:
  1. Richard H. Hunt

    1. Division of Gastroenterology, McMaster University Medical Centre, Hamilton, Canada

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    You can also search for this editor in PubMed   Google Scholar

  2. Guido N. J. Tytgat

    1. Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

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Table of contents (56 chapters)

  1. Front Matter

    Pages i-xix
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  2. Basic bacteriology of H. pylori

    1. Front Matter

      Pages 1-1
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    2. In vivo models of gastric Helicobacter infections

      • J. G. Fox
      Pages 3-27

    3. H. pylori species heterogeneity

      • F. Mégraud
      Pages 28-40

    4. H. pylori urease

      • H. L. T. Mobley, P. A. Foxall
      Pages 41-58

    5. Basic bacteriology of H. pylori: H. pylori colonization factors

      • A. Lee, H. Mitchell
      Pages 59-72

  3. Prevalence and mechanisms of spread of H. pylori

    1. Front Matter

      Pages 73-73
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    2. Epidemiology of H. pylori in Western countries

      • B. J. Marshall
      Pages 75-84

    3. H. pylori in developing countries

      • S. L. Hazell
      Pages 85-94

    4. Reinfection with H. pylori

      • D. Y. Graham, R. M. Genta
      Pages 113-120

  4. Prevalence and mechanisms of spread of H. pylori

    1. Prevalence/disease correlates of H. pylori

      • J. R. Lambert, S. K. Lin
      Pages 95-112

  5. Mechanisms of H. pylori induced damage

    1. Front Matter

      Pages 121-121
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    2. Breakdown of the mucus layer by H. pylori

      • J. Sarosiek, Z. Namiot, B. J. Marshall, D. A. Peura, R. L. Guerrant, D. Harlow et al.
      Pages 123-138

    3. Decreased hydrophobicity of gastroduodenal mucosa due to H. pylori infection in humans

      • T. C. Northfield
      Pages 139-147

    4. Adherence and internalization of H. pylori by epithelial cells

      • P. M. Sherman
      Pages 148-162

    5. Mechanisms of ammonia-induced gastric mucosal injury: role of glutathione and cysteine proteases

      • S. Szabo, S. Kusstatscher, L. Nagy, Zs. Sandor
      Pages 163-168

    6. Lipopolysaccharide (LPS)-related damage by H. pylori

      • A. Lee, A. P. Moran
      Pages 169-179

    7. The cpn60 heat shock protein homologue of H. pylori

      • B. E. Dunn
      Pages 180-187

    8. Gastric mucosal injury: interactions of mast cells, cytokines and nitric oxide

      • K. P. Rioux, C. M. Hogaboam, J. L. Wallace
      Pages 188-197

    9. H. pylori supernatant contains a novel chemotactic factor for monocytes different from FMLP

      • P. A. Anton, J. R. Reeve Jr, D. Quismorio, K. Smela, M. C. Territo, J. H. Walsh
      Pages 198-206
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Keywords

About this book

Helicobacter pylori has attracted widening interest from basic scientists and clinical investigators and the information on this organism is increasing exponentially. It is now accepted that H. Pylori is the most important cause of chronic active gastritis. Furthermore, data have confirmed a marked reduction in the relapse rate of both duodenal and gastric ulcer after eradication of the organism. These important clinical observations have served as a strong stimulus to the investigation of the basic mechanisms involved in the pathogenesis of H. pylori-associated inflammation and the subsequent alterations of gastroduodenal function and gastric mucosal architecture.
The book contains chapters by a multidisciplinary, international group of basic scientists and clinical investigators who focus on various microbiological aspects of H. pylori, on the role of H. pylori in peptic ulcer and gastric cancer, and the current status of therapy.
The book contains the proceedings of the conference on `Helicobacter pylori: Basic Mechanisms to Clinical Cure', held at Amelia Island, Florida, U.S.A., on November 3--6, 1993.

Reviews

`... I would recommend this book highly; it is an excellent and useful tool for professionals who study and treat Helicobacter pylori and for those who diagnose and manage diseases or the gastrointestinal tract.'
Annals of Oncology 6 (1995)

Editors and Affiliations

  • Division of Gastroenterology, McMaster University Medical Centre, Hamilton, Canada

    Richard H. Hunt

  • Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands

    Guido N. J. Tytgat

Bibliographic Information

  • Book Title: Helicobacter pylori

  • Book Subtitle: Basic Mechanisms to Clinical Cure

  • Editors: Richard H. Hunt, Guido N. J. Tytgat

  • DOI: https://doi.org/10.1007/978-94-011-1418-9

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1994

  • Hardcover ISBN: 978-0-7923-8838-8Published: 30 April 1994

  • Softcover ISBN: 978-94-010-4620-6Published: 28 October 2012

  • eBook ISBN: 978-94-011-1418-9Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIX, 612

  • Topics: Gastroenterology, Infectious Diseases, Pharmacology/Toxicology

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