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Basic bacteriology of H. pylori: H. pylori colonization factors

  • Chapter
Helicobacter pylori

Abstract

Helicobacter pylori is an unusual bacterial pathogen. This organism infects its host most probably in childhood and remains in most persons for life unless there has been specific H. pylori antimicrobial therapy or the stomach becomes an inhospitable environment due to such events as changes in the stomach due to long-term gastritis or surgery. Most pathogenic bacteria either infect the host transiently until they are eradicated due to the nonspecific and specific immune system, or they completely overwhelm the host, resulting in death. In a small number of chronic diseases such as tuberculosis or syphilis the organism may remain for long periods, but the numbers are greatly reduced, are difficult to find and are sequestered away in some inaccessible site. With respect to life in its chosen host H. pylori behaves more like a parasite. A characteristic of good parasites is that they are excellent colonizers.

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Authors
  1. A. Lee
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  2. H. Mitchell
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Editors and Affiliations

  1. Division of Gastroenterology, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada

    Richard H. Hunt (Professor of Medicine, Director) (Professor of Medicine, Director)

  2. Department of Gastroenterology and Hepatology, Academic Medical Centre, 9 Meibergdreef, 1105 AZ, Amsterdam, The Netherlands

    Guido N. J. Tytgat (Professor) (Professor)

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Lee, A., Mitchell, H. (1994). Basic bacteriology of H. pylori: H. pylori colonization factors. In: Hunt, R.H., Tytgat, G.N.J. (eds) Helicobacter pylori. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1418-9_4

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  • DOI: https://doi.org/10.1007/978-94-011-1418-9_4

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