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Novel Calcium-Binding Proteins

Fundamentals and Clinical Implications

  • Book
  • © 1991

Overview

Editors:
  1. Claus W. Heizmann

    1. Department of Pediatrics Division of Clinical Chemistry, University of Zürich, Zürich, Switzerland

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Table of contents (35 chapters)

  1. Front Matter

    Pages I-5
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  2. Preface

    1. Calcium-Binding Proteins: Past, Present and Future

      • Robert H. Wasserman
      Pages 7-12

    2. Acknowledgments

      • Claus W. Heizmann
      Pages 13-13

  3. Calcium Signaling by Calcium-Binding Proteins

    1. Front Matter

      Pages 15-15
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    2. The EF-Hand, Homologs and Analogs

      • Robert H. Kretsinger, David Tolbert, Susumu Nakayama, William Pearson
      Pages 17-37

    3. Calcium-Binding Proteins of the EF-Hand-Type and of the Annexin Family: A Survey

      • Claus W. Heizmann
      Pages 39-49

    4. Stains-All is a Dye that Probes the Conformational Features of Calcium Binding Proteins

      • Yogendra Sharma, Doraivajan Balasubramanian
      Pages 51-61

  4. EF-Hand Calcium-Binding Proteins: the S-100 Protein Family

    1. Front Matter

      Pages 63-63
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    2. The S-100 Protein Family: A Biochemical and Functional Overview

      • Dana C. Hilt, Douglas Kligman
      Pages 65-103

    3. p9Ka, A Calcium-Ion-Binding Protein of Cultured Myoepithelial Cells

      • Roger Barraclough, Philip S. Rudland
      Pages 105-123

    4. S-100-Related Proteins in Nerve Growth Factor-Induced Differentiation of PC12 Cells

      • Piotr Masiakowski, Eric M. Shooter
      Pages 125-137

    5. p11, A Member of the S-100 Protein Family, is Associated with the Tyrosine Kinase Substrate p36 (Annexin II)

      • Volker Gerke
      Pages 139-155

    6. Calcyclin, from Gene to Protein

      • Jacek Kuźnicki
      Pages 157-167

    7. Cloning and Characterization of a cDNA Encoding a Highly Conserved Ca2+-Binding Protein, Identified by an Anti-Prolactin Receptor Antibody

      • L. C. Murphy, Y. Gong, R. E. Reid
      Pages 169-190

    8. The Calgranulins, Members of the S-100 Protein Family: Structural Features, Expression, and Possible Function

      • David Longbottom, Veronica van Heyningen
      Pages 191-223

    9. MRP8 and MRP14, Two Calcium-Binding Proteins Expressed During Myelopoiesis

      • Eric Lagasse
      Pages 225-236

    10. Distribution of the Calcium-Binding Proteins MRP-8 and MRP-14 in Normal and Pathological Conditions: Relation to the Cystic Fibrosis Antigen

      • Josef Brüggen, Nico Cerletti
      Pages 237-247

  5. Novel Members of the EF-Hand Calcium-Binding Protein Family in Normal and Transformed Cells

    1. Front Matter

      Pages 249-249
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    2. Calretinin

      • John H. Rogers
      Pages 251-276

    3. Purification, Identification and Regional Localization of a Brain-Specific Calretinin-Like Calcium Binding Protein (Protein 10)

      • Lois Winsky, David M. Jacobowitz
      Pages 277-300
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Keywords

About this book

A wide variety of hormones, neurotransmitters and growth factors exert their cellular effects by reacting first with membrane receptors resulting in an increase of intracellular calcium and the cellular response. The calcium signal in the cell is mediated by the high-affinity calcium binding proteins (characterized by the EF-hand structural element), and by the calcium and phospholipid dependent proteins. Many of these have been discovered most recently. Their purification, distribution, protein and gene structures as well as their physiological roles are discussed. The book is of interest to biochemists and molecular biologists as well as to clinicians and the pharmaceutical industry who can apply the results in this field.

Editors and Affiliations

  • Department of Pediatrics Division of Clinical Chemistry, University of Zürich, Zürich, Switzerland

    Claus W. Heizmann

Bibliographic Information

  • Book Title: Novel Calcium-Binding Proteins

  • Book Subtitle: Fundamentals and Clinical Implications

  • Editors: Claus W. Heizmann

  • DOI: https://doi.org/10.1007/978-3-642-76150-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1991

  • Softcover ISBN: 978-3-642-76152-2Published: 14 December 2011

  • eBook ISBN: 978-3-642-76150-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 624

  • Topics: Biochemistry, general, Zoology, Pharmacology/Toxicology, Cell Biology, Cancer Research, Pharmacy

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