Overview
- Up-to-date information on the molecular basis of selected hematologic disorders
- Practical reference for molecular laboratory procedures
- Of interest to clinical oncologists and hematologists as well as to graduates in molecular medicine, human genetics and laboratory medicine
- Includes supplementary material: sn.pub/extras
Part of the book series: Principles and Practice (PRINCIPLES)
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Table of contents (29 chapters)
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Molecular Procedures Involved in Hematopoietic Stem Cell Transplantation
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Molecular Diagnostic Protocols
Keywords
About this book
This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.
Reviews
From the reviews:
“This book describes current diagnostic tools and clinical procedures used for hematological malignancies. … The goal was to meet the needs of both clinical hematologists who treat patients with leukemia, lymphoma, and/or multiple myeloma and those who study these diseases in the laboratory. … an excellent review of molecular biology for specific hematological malignancies and disorders. It also covers important molecular testing techniques that are commonly used in the diagnosis, management, and surveillance of these malignancies. … a valuable addition to any hematologist’s library.” (John Patrick Galvin, Doody’s Review Service, October, 2012)Editors and Affiliations
Bibliographic Information
Book Title: Molecular Aspects of Hematologic Malignancies
Book Subtitle: Diagnostic Tools and Clinical Applications
Editors: Michal Witt, Malgorzata Dawidowska, Tomasz Szczepanski
Series Title: Principles and Practice
DOI: https://doi.org/10.1007/978-3-642-29467-9
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2012
Hardcover ISBN: 978-3-642-29466-2Published: 01 July 2012
Softcover ISBN: 978-3-642-44522-4Published: 26 June 2015
eBook ISBN: 978-3-642-29467-9Published: 30 June 2012
Series ISSN: 1866-914X
Series E-ISSN: 1866-9158
Edition Number: 1
Number of Pages: X, 476
Topics: Molecular Medicine, Laboratory Medicine, Cancer Research, Hematology, Human Genetics