Overview
- Presents theoretical foundations of Systems Biology
- Lists applications in studies on human hosts, pathogens and associated diseases
- Topics discussed include computational modeling of multi-resistant bacteria, systems biology of cancer, systems immunology and networks in systems biology
Part of the book series: Computational Biology (COBO, volume 27)
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About this book
This book presents several chapters written by renowned experts in the field. Some topics discussed in depth in this book include: computational modeling of multiresistant bacteria, systems biology of cancer, systems immunology, networks in systems biology.
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Keywords
Table of contents (13 chapters)
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Fundamentals
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Applied Systems Biology
Editors and Affiliations
About the editors
Prof. Dr. Nicolas Carels is the coordinator of the Laboratory of Biological System Modeling (LMSB) from the Center for Technological Development in Health (CDTS) of Oswaldo Cruz Foundation. Since the 1990s, he accumulated expertise in the genetics, biotechnology and bioinformatics of plant systems. Morerecently due to the availability of high throughput datasets in the context of the post-genomics era, he dedicated his activities to the bioinformatics of diseases’ molecular networks in the context of translational medicine. He is also investigating the metagenomics of microbial communities in interaction with human protozoan parasites in invertebrate hosts.
Prof. Dr. Floriano Paes Silva Junior is the head of the Laboratory of Computational and Experimental Biochemistry of Drugs (LaBECFar) at Oswaldo Cruz Institute, FIOCRUZ. Dr. Silva-Jr has expertise on Medicinal Chemistry and Chemical Biology working on the interface between computational and experimental approaches for drug discovery. His contributions include discovery and biochemical characterization of new drug targets and bioactive compounds with relevance to both infectious and non-communicable diseases.Â
Bibliographic Information
Book Title: Theoretical and Applied Aspects of Systems Biology
Editors: Fabricio Alves Barbosa da Silva, Nicolas Carels, Floriano Paes Silva Junior
Series Title: Computational Biology
DOI: https://doi.org/10.1007/978-3-319-74974-7
Publisher: Springer Cham
eBook Packages: Computer Science, Computer Science (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2018
Hardcover ISBN: 978-3-319-74973-0Published: 06 July 2018
Softcover ISBN: 978-3-030-09117-0Published: 14 December 2018
eBook ISBN: 978-3-319-74974-7Published: 21 June 2018
Series ISSN: 1568-2684
Series E-ISSN: 2662-2432
Edition Number: 1
Number of Pages: XVIII, 259
Number of Illustrations: 16 b/w illustrations, 26 illustrations in colour
Topics: Computational Biology/Bioinformatics, Bioinformatics, Health Informatics, Cancer Research, Cell Biology