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Handbook of Life Course Health Development

  • Synthesizes research linking early life events with adult health conditions

  • Delineates the developmental origins of common chronic health conditions

  • Specifies processes by which both adversity and opportunity are embedded into developing bio-behavioral systems

  • Examines strategies that minimize the impact of adversity, increase protective factors, and target interventions to coincide with sensitive periods of development?

  • Includes supplementary material:

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xxiv
  2. Introduction to the Handbook of Life Course Health Development

    • Neal Halfon, Christopher B. Forrest, Richard M. Lerner, Elaine M. Faustman, Ericka Tullis, John Son
    Pages 1-16Open Access
  3. Emerging Frameworks

    1. Front Matter

      Pages 17-17
    2. The Emerging Theoretical Framework of Life Course Health Development

      • Neal Halfon, Christopher B. Forrest
      Pages 19-43Open Access
  4. Life Stages

    1. Front Matter

      Pages 45-45
    2. Preconception and Prenatal Factors and Metabolic Risk

      • Guoying Wang, Tami R. Bartell, Xiaobin Wang
      Pages 47-59Open Access
    3. Middle Childhood: An Evolutionary-Developmental Synthesis

      • Marco DelGiudice
      Pages 95-107Open Access
    4. Adolescent Health Development: A Relational Developmental Systems Perspective

      • Richard M. Lerner, Claire D. Brindis, Milena Batanova, Robert Wm. Blum
      Pages 109-121Open Access
    5. Emerging Adulthood as a Critical Stage in the Life Course

      • David Wood, Tara Crapnell, Lynette Lau, Ashley Bennett, Debra Lotstein, Maria Ferris et al.
      Pages 123-143Open Access
    6. Pregnancy Characteristics and Women’s Cardiovascular Health

      • Abigail Fraser, Janet M. Catov, Deborah A. Lawlor, Janet W. Rich-Edwards
      Pages 145-165Open Access
  5. The Life Course Origins and Consequences of Select Major Health Conditions and Issues

    1. Front Matter

      Pages 167-167
    2. Early in the Life Course: Time for Obesity Prevention

      • Summer Sherburne Hawkins, Emily Oken, Matthew W. Gillman
      Pages 169-196Open Access
    3. Pediatric Type 2 Diabetes: Prevention and Treatment Through a Life Course Health Development Framework

      • Pamela Salsberry, Rika Tanda, Sarah E. Anderson, Manmohan K. Kamboj
      Pages 197-236Open Access
    4. Life Course Health Development in Autism Spectrum Disorders

      • Irene E. Drmic, Peter Szatmari, Fred Volkmar
      Pages 237-274Open Access
    5. Self-Regulation

      • Megan McClelland, John Geldhof, Fred Morrison, Steinunn Gestsdóttir, Claire Cameron, Ed Bowers et al.
      Pages 275-298Open Access
    6. A Life Course Health Development Perspective on Oral Health

      • James J. Crall, Christopher B. Forrest
      Pages 299-320Open Access
    7. A Life Course Approach to Hearing Health

      • Shirley A. Russ, Kelly Tremblay, Neal Halfon, Adrian Davis
      Pages 349-373Open Access
    8. Chronic Kidney Disease: A Life Course Health Development Perspective

      • Patrick D. Brophy, Jennifer R. Charlton, J. Bryan Carmody, Kimberly J. Reidy, Lyndsay Harshman, Jeffrey Segar et al.
      Pages 375-401Open Access

About this book

This book is open access under a CC BY 4.0 license.

​This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint.  In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy.

Topics featured in the Handbook include: 

  • The prenatal period and its effect on child obesity and metabolic outcomes.
  • Pregnancy complications and their effect on women’s cardiovascular health.
  • A multi-level approach for obesity prevention in children.
  • Application of the LCHD framework to autism spectrum disorder.
  • Socioeconomic disadvantage and its influence on health development across the lifespan.
  • The importance of nutrition to optimal health development across the lifespan.

The Handbook of Life Course Health Development is a must-have resource for researchers, clinicians/professionals, and graduate students in developmental psychology/science; maternal and child health; social work; health economics; educational policy and politics; and medical law as well as many interrelated subdisciplines in psychology, medicine, public health, mental health, education, social welfare, economics, sociology, and law.


  • ACEs and health development science
  • Adverse childhood experiences and health development science
  • Autism and health across the life course
  • Biological embedding and health outcomes
  • Chronic kidney disease across the life course
  • Community and heath development
  • Developmental origins of chronic illnesses
  • Diabetes and life course health
  • Family and health development
  • Fetal programming and health development
  • Health disparities across the lifespan
  • Hearing loss and health development
  • Life course health development science
  • MCH and health development science
  • Maternal and child health over the life course
  • Nutrition and health across the lifespan
  • Obesity and health
  • Oral health across the life course
  • Self-regulation and health
  • Spina Bifada across the life course

Editors and Affiliations

  • Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, USA

    Neal Halfon

  • Applied Clinical Research Center Children’s Hospital of Philadelphia, Philadelphia, USA

    Christopher B. Forrest

  • Tufts University, Medford, USA

    Richard M. Lerner

  • Institute for Risk Analysis and Risk Communication, Department of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, USA

    Elaine M. Faustman

About the editors

Neal Halfon, M.D., M.P.H., is the director of the UCLA Center for Healthier Children, Families and Communities. He is also a professor of pediatrics in the David Geffen School of Medicine at UCLA, of health policy and management in the UCLA Fielding School of Public Health, and of public policy in the UCLA Luskin School of Public Affairs. Dr. Halfon’s research has spanned clinical, health services, epidemiologic and health policy domains. For more than a decade, he has worked with national, state and local initiatives aimed at improving early childhood systems. Dr. Halfon has also played a significant role in developing new conceptual frameworks for the study of health and health care, including the Life Course Health Development (LCHD) framework. In 2006Halfon received the Academic Pediatric Associations Annual Research Award for his life time contributions to child health research.  He received his M.D. at the University of California, Davis, and M.P.H. at University of California, Berkeley. He completed his pediatric residency at UC San Diego and UC San Francisco. Dr. Halfon was also Robert Wood Johnson Clinical Scholar at UC San Francisco.

Christopher Forrest, M.D., Ph.D., is Professor of Pediatrics and Health Care Management at the Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania. He is the Director of the CHOP Center for Applied Clinical Research, which uses life course health development science to adva^5 million children) that conducts patient-centered outcomes research among children and youth. He is the Chair of the Research Committee for PCORnet, the national clinical research network funded by PCORI. He also chairs the Steering Committee for the NIH program called PEPR, which is conducting longitudinal studies on person-reported outcome measures in children with chronic conditions. Dr. Forrest received his BA and MD degrees from Boston University and completed his PhD in Health Policy and Management at Johns Hopkins School of Public Health. 

Richard M. Lerner, Ph.D., is the Bergstrom Chair in Applied Developmental Science and the Director of the Institute for Applied Research in Youth Development at Tufts University. He went from kindergarten through Ph.D. within the New York City public schools, completing his doctorate at the City University of New York in 1971 in developmental psychology. Dr. Lerner has more than 700 scholarly publications, including 80 authored or edited books. He was the founding editor of the Journal of Research on Adolescence and Applied Developmental Science, which he continues to edit. He was a 1980-81 fellow at the Center for Advanced Study in the Behavioral Sciences and is a fellow of the American Association for the Advancement of Science, the American Psychological Association, and the Association for Psychological Science. Dr. Lerner is known for his theory of relations between life-span human development and social change and for his research about the relations between adolescents and their peers, families, schools, and communities. His work integrates the study of public policies and community-based programs with the promotion of positive youth development and youth contributions to civil society. He is married to Dr. Jacqueline V. Lerner, Professor in the Department of Applied Developmental and Educational Psychology in the Lynch School of Education at Boston College. They live in Wayland, Massachusetts. They have three children, Justin, a director and screen writer living in Los Angeles, Blair, an advertising executive at Media Contacts in Boston, and Jarrett, a novelist and editor living in Boston.

Elaine M. Faustman, Ph.D., DABT, is Professor in the Department of Environmental and Occupational Health and Director of the Institute for Risk Analysis and Risk Communication at the School of Public Health and Community Medicine at the University of Washington. She directs the NIEHS and EPA funded Center for Child Environmental Health Risks Research and led the Pacific Northwest Center for the National Children’s Study. She is an elected fellow of both the American Association for the Advancement of Science and the Society for Risk Analysis. Dr. Faustman is an affiliate professor in the School of Public Affairs at the University of Washington and has been an affiliate Professor in the Department of Engineering and Public Policy at Carnegie-Mellon University. She has served on the National Toxicology Program Board of Scientific Counselors, the National Academy of Sciences Committee on Toxicology, the Institute of Medicine Upper Reference Levels Subcommittee of the Food and Nutrition Board, and on numerous editorial boards. Dr. Faustman chaired the National Academy of Sciences Committee on Developmental Toxicology. She has or is currently serving on the executive boards of the Society of Toxicology, the Society for Risk Analysis and NIEHS Council. She is past President of the Teratology Society. Her research interests include understanding mechanisms that put children and the public at risk from environmental agents. Currently she is serving on the Committee on NAS Gulf War and Health, Volume 11: Generational Health Effects of Serving in the Gulf War. In particular, Dr. Faustman is interested in the molecular and cellular mechanisms of developmental and reproductive toxicants, characterizing in vitro techniques for developmental toxicology assessment, and development of biologically based dose-response models for non-cancer risk assessment. Dr. Faustman’s research expertise includes development of decision-analytic tools for communicating and translating new scientific findings into risk assessment and risk management decisions.

Bibliographic Information

  • Book Title: Handbook of Life Course Health Development

  • Editors: Neal Halfon, Christopher B. Forrest, Richard M. Lerner, Elaine M. Faustman

  • DOI:

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s) 2018

  • License: CC BY

  • Hardcover ISBN: 978-3-319-47141-9Published: 07 December 2017

  • Softcover ISBN: 978-3-319-83665-2Published: 05 September 2018

  • eBook ISBN: 978-3-319-47143-3Published: 20 November 2017

  • Edition Number: 1

  • Number of Pages: XXIV, 664

  • Number of Illustrations: 26 b/w illustrations, 22 illustrations in colour

  • Topics: Public Health, Developmental Psychology, Social Work, Health Economics, Educational Policy and Politics, Medical Law

Buy it now

Buying options

Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 59.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access