Overview
Focus is set on platelet biogenesis
Describes cell and molecular platelet biology as well as clinical aspects
Includes the use of diverse animal models for platelet research
Written by internatinoal leading figures
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About this book
This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and research. It represents an indispensable tool for research scientists in biomedicine, vascular biology, hematopoiesis and hemostasis and specifically for scientists in platelet research, as well as for clinicians in the field of hematology and transfusion medicine.
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Keywords
Table of contents (21 chapters)
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Platelets in Health and Disease
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Future Perspectives for Platelet Biogenesis
Reviews
Editors and Affiliations
About the editors
P.D. Dr. Harald Schulze, studied biochemistry at the University of Hannover and at the Hannover Medical Faculty. As PostDoctoral Assistant at the Dana-Farber Cancer Insitute, Harvard Medical School, Boston, USA, he performed research on megakaryocytes and platelet biogenesis. Since 2005 Harald Schulze is Group leader and Head of the Laboratory for Pediatric Molecular Biology, Charité in Berlin. His group studies the basic mechanisms of platelet production from megakaryocytes. Another focus of the laboratory lies in the analysis of the rare congenital disorder, the TAR syndrome, which is based on a defective mechanism in hematopoiesis.
Dr. Joseph E. Italiano Jr. received his PhD from Florida State University and trained as a Post-Doctoral Fellow in the Division of Hematology at Brigham and Women’s Hospital from 1998-2000. He is currently Associate Professor of Medicine with appointments in the Division of Hematology at Brigham and Women’s Hospital, the Vascular Biology Program at Children’s Hospital Boston, and Harvard Medical School. His research focuses on how megakaryocytes produce platelets and how platelets regulate new blood vessel growth.
Bibliographic Information
Book Title: Molecular and Cellular Biology of Platelet Formation
Book Subtitle: Implications in Health and Disease
Editors: Harald Schulze, Joseph Italiano
DOI: https://doi.org/10.1007/978-3-319-39562-3
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-39560-9Published: 15 February 2017
Softcover ISBN: 978-3-319-81914-3Published: 17 July 2018
eBook ISBN: 978-3-319-39562-3Published: 07 February 2017
Edition Number: 1
Number of Pages: X, 460
Number of Illustrations: 15 b/w illustrations, 41 illustrations in colour
Topics: Human Physiology, Hematology, Cell Biology, Gene Therapy, Molecular Medicine, Blood Transfusion Medicine