Overview
- Editors:
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Mohamed Al-Rubeai
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University College Dublin, Dublin, Ireland
- This is a book designed specifically to provide powerful research opportunities for those interested in perusing work in large scale production of stem cells for clinical application
- This book is specially formatted so that it is not only a source on stem cell biology and therapeutic application but also a good foundation for understanding basic regenerative medicine
- Contributions by leading international investigators from wide backgrounds/interests and geographical locations
- Includes supplementary material: sn.pub/extras
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Table of contents (23 chapters)
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- Volker Jäger, Konrad Büssow, Thomas Schirrmann
Pages 27-64
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- Jeffrey J. Chalmers, Ningning Ma
Pages 169-183
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- Sebastian Schwamb, Robert Puskeiler, Philipp Wiedemann
Pages 185-221
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- Maureen Spearman, Michael Butler
Pages 237-258
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- Nishikant P. Shirsat, Niall J. English, Brian Glennon, Mohamed Al-Rubeai
Pages 259-326
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- Darrin Kuystermans, Mohamed Al-Rubeai
Pages 327-372
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- Peter M. O’Callaghan, Andrew J. Racher
Pages 373-406
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- Stephan C. Kaiser, Matthias Kraume, Dieter Eibl, Regine Eibl
Pages 445-500
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- Laura A. Palomares, Mauricio Realpe, Octavio T. Ramírez
Pages 501-519
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- João V. Sá, Tiago M. Duarte, Manuel J. T. Carrondo, Paula M. Alves, Ana P. Teixeira
Pages 521-539
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- Ana Carina Silva, António Roldão, Ana Teixeira, Paulo Fernandes, Marcos F. Q. Sousa, Paula M. Alves
Pages 541-563
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- Eric Baek, Che Lin Kim, Jin Hyoung Park, Gyun Min Lee
Pages 565-590
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- Kelley Heffner, Christian Schroeder Kaas, Amit Kumar, Deniz Baycin-Hizal, Michael Betenbaugh
Pages 591-614
About this book
Animal cells are the preferred “cell factories” for the production of complex molecules and antibodies for use as prophylactics, therapeutics or diagnostics. Animal cells are required for the correct post-translational processing (including glycosylation) of biopharmaceutical protein products. They are used for the production of viral vectors for gene therapy. Major targets for this therapy include cancer, HIV, arthritis, cardiovascular and CNS diseases and cystic fibrosis. Animal cells are used as in vitro substrates in pharmacological and toxicological studies. This book is designed to serve as a comprehensive review of animal cell culture, covering the current status of both research and applications. For the student or R&D scientist or new researcher the protocols are central to the performance of cell culture work, yet a broad understanding is essential for translation of laboratory findings into the industrial production. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field to produce state-of-the-art collection of current research. A major reference volume on cell culture research and how it impacts on production of biopharmaceutical proteins worldwide, the book is essential reading for everyone working in cell culture and is a recommended volume for all biotechnology libraries.
Editors and Affiliations
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University College Dublin, Dublin, Ireland
Mohamed Al-Rubeai