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  • Book
  • Open Access
  • © 2015

High Density Lipoproteins

From Biological Understanding to Clinical Exploitation

  • Summarizes latest results of the European network on HDL

  • Broadens your understanding of both clinical and molecular biology issues relevant to HDL

  • Gives insight into latest treatments of HDL

  • Includes supplementary material: sn.pub/extras

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 224)

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-xiii
  2. Physiology of HDL

    1. Front Matter

      Pages 1-1
    2. Structure of HDL: Particle Subclasses and Molecular Components

      • Anatol Kontush, Mats Lindahl, Marie Lhomme, Laura Calabresi, M. John Chapman, W. Sean Davidson
      Pages 3-51Open Access
    3. HDL Biogenesis, Remodeling, and Catabolism

      • Vassilis I. Zannis, Panagiotis Fotakis, Georgios Koukos, Dimitris Kardassis, Christian Ehnholm, Matti Jauhiainen et al.
      Pages 53-111Open Access
    4. Regulation of HDL Genes: Transcriptional, Posttranscriptional, and Posttranslational

      • Dimitris Kardassis, Anca Gafencu, Vassilis I. Zannis, Alberto Davalos
      Pages 113-179Open Access
    5. Cholesterol Efflux and Reverse Cholesterol Transport

      • Elda Favari, Angelika Chroni, Uwe J. F. Tietge, Ilaria Zanotti, Joan Carles Escolà-Gil, Franco Bernini
      Pages 181-206Open Access
    6. Functionality of HDL: Antioxidation and Detoxifying Effects

      • Helen Karlsson, Anatol Kontush, Richard W. James
      Pages 207-228Open Access
  3. Pathology of HDL

    1. Front Matter

      Pages 257-257
    2. Mouse Models of Disturbed HDL Metabolism

      • Menno Hoekstra, Miranda Van Eck
      Pages 301-336Open Access
    3. Dysfunctional HDL: From Structure-Function-Relationships to Biomarkers

      • Meliana Riwanto, Lucia Rohrer, Arnold von Eckardstein, Ulf Landmesser
      Pages 337-366Open Access
  4. Possible Indications and Target Mechanisms of HDL Therapy

    1. Front Matter

      Pages 367-367
    2. HDL and Atherothrombotic Vascular Disease

      • Wijtske Annema, Arnold von Eckardstein, Petri T. Kovanen
      Pages 369-403Open Access
    3. HDLs, Diabetes, and Metabolic Syndrome

      • Peter Vollenweider, Arnold von Eckardstein, Christian Widmann
      Pages 405-421Open Access
    4. High-Density Lipoprotein: Structural and Functional Changes Under Uremic Conditions and the Therapeutic Consequences

      • Mirjam Schuchardt, Markus Tölle, Markus van der Giet
      Pages 423-453Open Access
    5. Impact of Systemic Inflammation and Autoimmune Diseases on apoA-I and HDL Plasma Levels and Functions

      • Fabrizio Montecucco, Elda Favari, Giuseppe Danilo Norata, Nicoletta Ronda, Jerzy-Roch Nofer, Nicolas Vuilleumier
      Pages 455-482Open Access
    6. HDL in Infectious Diseases and Sepsis

      • Angela Pirillo, Alberico Luigi Catapano, Giuseppe Danilo Norata
      Pages 483-508Open Access
    7. High-Density Lipoproteins in Stroke

      • Olivier Meilhac
      Pages 509-526Open Access

About this book

In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation.

The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.

Editors and Affiliations

  • University Hospital Zurich Institute of Clinical Chemistry, Zurich, Switzerland

    Arnold von Eckardstein

  • University of Crete Medical School, Iraklion, Crete, Greece

    Dimitris Kardassis

Bibliographic Information

  • Book Title: High Density Lipoproteins

  • Book Subtitle: From Biological Understanding to Clinical Exploitation

  • Editors: Arnold von Eckardstein, Dimitris Kardassis

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-319-09665-0

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and the Author(s) 2015

  • License: CC BY-NC

  • Hardcover ISBN: 978-3-319-09664-3Published: 13 January 2015

  • Softcover ISBN: 978-3-319-34861-2Published: 14 October 2016

  • eBook ISBN: 978-3-319-09665-0Published: 18 December 2014

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XIII, 694

  • Number of Illustrations: 3 b/w illustrations, 37 illustrations in colour

  • Topics: Pharmacology/Toxicology, Molecular Medicine, Human Physiology, Immunology, Cell Biology

Buy it now

Buying options

Softcover Book USD 59.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 59.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access