Overview
- Covers basic principles, advanced clinical management, evidence-based approaches and translational research
- Comprehensive, highly referenced, resource to intrathecal therapies
- Authored by worldwide leaders in the field
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Table of contents (44 chapters)
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Front Matter
Keywords
About this book
This book is a comprehensive reference of the neuraxial route for the delivery of therapeutics. It reviews the historical evolution of this approach from its inception in the later 1800's to present day. This amply referenced text covers basic discussions of spinal anatomy, embryogenesis, neuraxial vascularity, cerebrospinal fluid flow dynamics and parenchymal molecule movement. The pharmacokinetic and pharmacodynamic properties of different intrathecal agents are explored in detail with particular reference to clinical correlates in pain and spasticity. Particular attention is paid to the issues relevant to preclinical models of intrathecal delivery and the assessment of spinal pathologies arising from acute and chronic intrathecal drug delivery. Chapters provide essential discussions of clinical aspects of patient care, including patient evaluation and screening, trialing and device management, troubleshooting problems and addressing complications, best practices, cost-effectiveness and future of the therapy.
Clinicians and researchers who practice intrathecal therapy and study neuraxial mechanisms will find Neuraxial Therapeutics, to be an invaluable guide to this treatment modality.
Editors and Affiliations
About the editors
Salim M. Hayek, MD, PhD
University Hospitals of Cleveland
Division of Pain Medicine
Department of Anesthesiology
Cleveland, OH USA
Tony L. Yaksh, PhD
University of California, San Diego
Department of Anesthesiology and Pharmacology
La Jolla, CA USA
Bibliographic Information
Book Title: Neuraxial Therapeutics
Book Subtitle: A Comprehensive Guide
Editors: Tony Yaksh, Salim Hayek
DOI: https://doi.org/10.1007/978-3-031-39558-1
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Nature Switzerland AG 2023
Hardcover ISBN: 978-3-031-39557-4Published: 03 January 2024
Softcover ISBN: 978-3-031-39560-4Due: 03 February 2024
eBook ISBN: 978-3-031-39558-1Published: 02 January 2024
Edition Number: 1
Number of Pages: XIX, 830
Number of Illustrations: 87 b/w illustrations, 163 illustrations in colour
Topics: Pain Medicine, Anesthesiology, Neurology