Immunology of Rheumatic Diseases

  • Sudhir Gupta
  • Norman Talal

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Basic Mechanisms

    1. Front Matter
      Pages 1-1
    2. Gerald T. Nepom, John A. Hansen
      Pages 3-19
    3. Sudhir Gupta
      Pages 21-83
    4. Sudhir Gupta
      Pages 85-108
    5. Sudhir Gupta
      Pages 109-139
  3. Autoimmunity

    1. Front Matter
      Pages 165-165
    2. Sherman Fong, Dennis A. Carson, John H. Vaughan
      Pages 167-196
    3. Gordon C. Sharp, Margaret A. Alspaugh
      Pages 197-219
    4. Bevra H. Hahn
      Pages 221-235
    5. Ken D. Pischel, Harry G. Bluestein
      Pages 237-249
    6. G. R. V. Hughes, E. N. Harris, A. E. Gharavi
      Pages 251-269
    7. Marc Feldmann, Deborah Doniach, Gian Franco Bottazzo
      Pages 271-300
    8. David E. Trentham
      Pages 301-323
  4. Classical Concepts of Rheumatic Diseases

    1. Front Matter
      Pages 325-325
    2. Frank R. Schmid
      Pages 367-395
    3. J. Eugene Huffstutter, E. Carwile LeRoy
      Pages 397-423
    4. Daniel J. McCarty
      Pages 425-463

About this book


Recent developments in basic science and clinical rheumatology make it appropriate at this time to create a volume devoted to the immunology of rheumatic diseases. The impact of molecular biology, gene cloning, and new technologies for establishing hybridomas and T-cell lines in the laboratory is now beginning to be felt in clinical medicine. There is a general air of excitement and a feeling that we stand on the threshold of a new era in molecular medicine and clinical science. It is this excitement that we have tried to capture in this book. This volume is divided into five sections entitled Basic Mechanisms, Autoimmunity, Classical Concepts of Rheumatic Diseases, Pathogenetic Mechanisms, and Therapy. This is not an arbitrary arrangement but represents our belief that from an understanding of basic mechanisms of disease pathogenesis will come new and more successful forms of treatment for the sufferers of rheumatic disorders. We have tried in the selection of authors to choose internationally recognized experts who have both a scientific and a clinical orientation to their subjects. We believe the marriage of clinical and basic disciplines represents the best hope for rapid knowledge transfer from the laboratory to the clinic, where such knowledge can be used to improve patient health.


autoimmunity diseases molecular biology pathogenesis rheumatic diseases

Editors and affiliations

  • Sudhir Gupta
    • 1
  • Norman Talal
    • 2
  1. 1.College of MedicineUniversity of CaliforniaIrvineUSA
  2. 2.Health Science CenterUniversity of TexasSan AntonioUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1985
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-9509-9
  • Online ISBN 978-1-4613-2493-5
  • About this book