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Translational Methods for PTSD Research

  • Book
  • © 2023

Overview

Editors:
  1. Graziano Pinna

    1. Psychiatric Institute, University of Chicago, Chicago, USA

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 198)

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Table of contents (15 protocols)

  1. Front Matter

    Pages i-xviii
    Download chapter PDF

  2. Translational Model of Infant PTSD Induction: Methods for Infant Fear Conditioning

    • Roseanna M. Zanca, Sara Stanciu, Islam Ahmed, Christopher K. Cain, Regina M. Sullivan
    Pages 1-22

  3. Periadolescent Social Isolation Effects on Extinction of Conditioned Fear

    • Katherine Drummond, Jee Hyun Kim
    Pages 23-35

  4. Using Virtual Reality to Study Fear and Extinction in Children and Adolescents

    • Hilary A. Marusak, Craig Peters, Christine A. Rabinak
    Pages 37-49

  5. Assessing the Role of Sleep in the Regulation of Emotion in PTSD

    • Ihori Kobayashi, Mariana E. Pereira, Kilana D. Jenkins, Fred L. Johnson III, Edward F. Pace-Schott
    Pages 51-96

  6. Pavlovian Conditioning and Extinction Methods for Studying the Neurobiology of Fear Learning in PTSD

    • Dylan B. Miller, Madeleine M. Rassaby, Zhenfu Wen, Mohammed R. Milad
    Pages 97-115

  7. Reconciling Translational Disparities Between Empirical Approaches to Better Understand PTSD

    • Seth D. Norrholm, Timothy J. Cilley Jr., Tanja Jovanovic
    Pages 117-134

  8. An Integrative Model for Endophenotypes Relevant to Posttraumatic Stress Disorder (PTSD): Detailed Methodology for Inescapable Tail Shock Stress (IS) and Juvenile Social Exploration (JSE)

    • Nathan D. Andersen, John D. Sterrett, Gabriel W. Costanza-Chavez, Cristian A. Zambrano, Michael V. Baratta, Matthew G. Frank et al.
    Pages 135-168

  9. Apolipoprotein E Isoform-Related Translational Measures in PTSD Research

    • Eileen Ruth Samson Torres, Andrea E. DeBarber, Jacob Raber
    Pages 169-189

  10. Stress Immobilization Inducing Fear Extinction Deficits in Male and Female Mice

    • Eric Raul Velasco, Antonio Florido, Ignacio Javier Marin-Blasco, Patricia Molina, Laura Perez-Caballero, Raul Andero
    Pages 191-201

  11. 5-HT Neural System Abnormalities in PTSD Model Rats

    • Hiroki Shikanai, Hirokazu Matsuzaki, Rina Kasai, Shota Kusaka, Tsugumi Shindo, Takeshi Izumi
    Pages 203-213

  12. Animal Models of PTSD: The Role of Fear Conditioning

    • Mariella B. L. Careaga, Carlos Eduardo Neves Girardi, Deborah Suchecki
    Pages 215-229

  13. Combining Virtual Reality Exposure Therapy with Non-invasive Brain Stimulation for the Treatment of Post-traumatic Stress Disorder and Related Syndromes: A Perspective

    • Carmelo M. Vicario, Mohammad A. Salehinejad, Chiara Lucifora, Gabriella Martino, Alessandra M. Falzone, G. Grasso et al.
    Pages 231-245

  14. Associating Aversive Task Exposure with Pharmacological Intervention to Model Traumatic Memories in Laboratory Rodents

    • Lucas Gazarini, Cristina A. J. Stern, Leandro J. Bertoglio
    Pages 247-304

  15. Loudness Dependence of Auditory Evoked Potentials: A Promising Pre-treatment Predictor of Selective Serotonin Reuptake Inhibitor Response

    • Suzanne L. Pineles, Shivani Pandey, Rachel Shor, Ronnie F. Abi-Raad, Matthew O. Kimble, Scott P. Orr
    Pages 305-324

  16. Preclinical Methods of Neurosteroid-Induced Facilitation of Fear Extinction and Fear Extinction Retention

    • Luca Spiro Santovito, Graziano Pinna
    Pages 325-348

  17. Back Matter

    Pages 349-350
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Keywords

About this book

This volume explores the latest experimental techniques in animal models of PTSD and humans affected by PTSD. The methods discussed in this book cover topics such as translational research; addressing sex differences; highlighting the state-of-the-art of biomarker discovery in the development and maintenance of PTSD; and looks at new promising agents to enhance fear extinction retention that may help millions of individuals that suffer from this debilitating disorder worldwide. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. 


Authoritative and thorough, Translational Methods for PTSD Research is a valuable resource that will help researchers understand and learn more about this important disorder.


Editors and Affiliations

  • Psychiatric Institute, University of Chicago, Chicago, USA

    Graziano Pinna

Bibliographic Information

  • Book Title: Translational Methods for PTSD Research

  • Editors: Graziano Pinna

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-0716-3218-5

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2023

  • Hardcover ISBN: 978-1-0716-3217-8Published: 27 May 2023

  • Softcover ISBN: 978-1-0716-3220-8Due: 27 June 2023

  • eBook ISBN: 978-1-0716-3218-5Published: 26 May 2023

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XVIII, 350

  • Number of Illustrations: 1 b/w illustrations

  • Topics: Neurosciences, Biomedicine, general

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