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About this book
Sphingolipids are fundamental to the structures of cell membranes, lipoproteins, and the stratum cornea of the skin. Many complex sphingolipids as well as simpler sphingoid bases and derivatives are highly bioactive as extra- and intracellular regulators of growth, differentiation, migration, survival, senescence, and numerous cellular responses to stress. This book provides many examples of exciting new developments in sphingolipid biology/sphingolipidology that are changing our understanding of how multicellular organisms grow, develop, function, age, and die. Key areas addressed include sphingolipid biosynthesis, transport and membrane organization/lipid rafts; genetic approaches to understanding the roles of membrane sphingolipid biosynthesis; sphingolipid metabolism, specific G protein-coupled receptors (GPCRs), and signal transduction; and sphingolipid-associated disease and drug development.
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Table of contents (39 chapters)
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Overview
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Biosynthesis, Transport of Sphingolipids
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Generation and Degradation of Sphingolipid Signaling Molecules
Editors and Affiliations
Bibliographic Information
Book Title: Sphingolipid Biology
Editors: Yoshio Hirabayashi, Yasuyuki Igarashi, Alfred H. Merrill
DOI: https://doi.org/10.1007/4-431-34200-1
Publisher: Springer Tokyo
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Tokyo 2006
Hardcover ISBN: 978-4-431-34198-7Published: 19 July 2006
Softcover ISBN: 978-4-431-54666-5Published: 02 December 2014
eBook ISBN: 978-4-431-34200-7Published: 31 December 2007
Edition Number: 1
Number of Pages: XXV, 531
Topics: Cell Biology, Biochemistry, general