Abstract
Non-α-tocopherols are hydroxymethylated and hydrogenated to produce α-tocopherol in one pot process by simultaneously reacting with paraformaldehyde and hydrogen in the presence of catalysts of benzenesulfonic acid and 5% Pd/C in an autoclave. Effects of various operation conditions have been studied. The preferable reaction conditions are: temperature 180 °C to 200°C, pressure 5.0 MPa, acid concentration 0.5 g/100 ml ethanol, mass ratio of Pd/C to tocopherols 7.1 g/100 g, and reaction time 5.0 h. A product with α-tocopherol content of 80% was obtained by using a raw material with a total tocopherols content of 80.54%. The conversion of non-α-tocopherols is almost 100%, and the mole yield of α-tocopherol is more than 90%.
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Project (No. 001103231-01, 02) supported by the Natural Science Foundation of Zhejiang Province, China
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Yang, Yw., Wen, Gd., Wu, Cj. et al. Preparation of natural α-tocopherol from non-α-tocopherols. J. Zheijang Univ.-Sci. 5, 1524–1527 (2004). https://doi.org/10.1631/jzus.2004.1524
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DOI: https://doi.org/10.1631/jzus.2004.1524