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Electrochemical characterization of poly(3,4-ethylenedioxythiophene)/κ-carrageenan as a biocompatible conductive coat for biologic applications

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Abstract

Poly(3,4-ethylenedioxythiophene) (PEDOT) is synthesized through a micellar dispersion that allows incorporation of biomolecules into this conductive polymer layer. A PEDOTiK-carrageenan (κC) system was obtained by electrodeposition and it was compared with a standard PEDOT:sodium dodecyl sulfate electrode coat. The electrochemical behavior and the oxidation level after 1000 cycles were studied through cyclic voltammetry and μRaman spectroscopy. The oxidation ratio in the PEDOT increased while electrochemical activity decreased in both cases. Moreover, the PEDOT:κC system allowed the immobilization of the acetylcholinesterase enzyme, which retained its activity. The unique combination of properties is a key feature in the bioelectronics field.

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ACKNOWLEDGMENTS

This work was supported by the Consejo Nacional de Rectores (CONARE), Tecnológico de Costa Rica (TEC), and Vicerrectoría de Vida Estudiantil y Servicios Académicos (VIESA). The authors would like to thank Centro de Investigación y Extensión en Materiales (CIEMTEC).

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Authors and Affiliations

  1. Escuela de Ciencia e Ingeniería de Materiales, Institute Tecnológico de Costa Rica, 159-7050, Cartago, Costa Rica

    Priscila Hernandez-Suarez & Fernando Alvarado

  2. Escuela de Biologia, Institute Tecnológico de Costa Rica, 159-7050, Cartago, Costa Rica

    Karla Ramirez & E. Avendano

  3. Centra de Investigación en Ciencia e Ingenierfa de Materiales CICIMA, Universidad de Costa Rica, 2060, San José, Costa Rica

    E. Avendano

  4. Centra de Investigación y de Servicios Químicos y Microbiológicos CEQIATEC, Escuela de Química, Institute Tecnológico de Costa Rica, 159-7050, Cartago, Costa Rica

    Ricardo Starbird

Authors
  1. Priscila Hernandez-Suarez
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  2. Karla Ramirez
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  3. Fernando Alvarado
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  4. E. Avendano
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Corresponding authors

Correspondence to Priscila Hernandez-Suarez or Ricardo Starbird.

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The supplementary material for this article can be found at https://doi.org/10.1557/mrc.2018.189.

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Hernandez-Suarez, P., Ramirez, K., Alvarado, F. et al. Electrochemical characterization of poly(3,4-ethylenedioxythiophene)/κ-carrageenan as a biocompatible conductive coat for biologic applications. MRS Communications 9, 218–223 (2019). https://doi.org/10.1557/mrc.2018.189

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