Skip to main content
SpringerLink
Log in

Studies on the Interaction of Water-Soluble Fullerols with BSA and the Effects of Metallic Ions

  • Published:
MRS Online Proceedings Library Aims and scope

Abstract

The interaction of water-soluble C60 derived fullerols with bovine serum albumin (BSA) in physiological environment was studied in detail by the fluorescence method. Experiments showed that the interaction of fullerols with BAS is mainly in the manner of non-covalent hydrogen bond. Based on the measurements of fluorescence intensity, the apparent binding constant K and the binding site number n were obtained with K=4000 and n=1, and the energy transfer efficiency in the reaction is 0.63. Besides, the effects of metallic ions such as Cu2+, Fe3+ and Cr(VI) on the interaction of fullerols with BSA were investigated. It was found that the effects of the metallic ions are quite different from each other. Low concentrations of Cu2+ can promote the interactions between fullerols and BSA, while high concentrations of Fe3+ or Cr(VI) favorite the interactions between fullerols and BSA.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Y. Wang, L.T. Cheng, J. Phys. Chem., 96(4), 1530 (1992)

    Google Scholar 

  2. R. Sijbesma, G. Srdannov, F. Wudl, J.A. Castoro, C. Wilkins, S.H. Friedman, D.L. De Camp and G.L. Kenyon, J. Am. Chem. Soc., 115(15), 6510 (1993)

    Google Scholar 

  3. L.Y. Chiang, F.G. Lu, J.T. Lin, J. Chem. Soc., Chem. Commun., 12, 1283 (1995)

    Google Scholar 

  4. Y. M. She, Y. P. Ji, Y. F. He and S. Y. Liu, Chem. J. Chinese Univ., 19(11), 1735 (1998)

    Google Scholar 

  5. X.Q. Yan, X.G. Liu, J.L. Qiao, W.J. Jin and B.S. Xu, International Journal of Materials and Product Technology, (2001) accepted

    Google Scholar 

  6. T.B. Li, K.X. Huang, X.H. Li, H.Y. Jiang, J. Li, X. Z. Yan, J. Cai and S.K. Zhao, Chem. J. Chinese Univ., 19(6), 858 (1998)

    Google Scholar 

  7. G.Z. Chen, X.Z. Huang, and J.G. Xu, in The Development of Fluorescence Analysis, (Xiamen University Press, Fujian, China, 1991), p174

    Google Scholar 

  8. X.Z. Feng, R.X. Jin, Y. Qu and H.W. He, Chem. J. Chinese Univ., 17(6), 866 (1996)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. College of Materials Science and Engineering, Taiyuan, Shanxi, 030024, China

    Xu Bingshe, Liu Xuguang & Yan Xiaoqin

  2. College of Science, Taiyuan Shanxi, China, 030024

    Qiao Jinli

  3. Department of Chemistry, Shanxi University, Taiyuan Shanxi, China, 030006

    Jin Weijun

Authors
  1. Xu Bingshe
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Liu Xuguang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yan Xiaoqin
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Qiao Jinli
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jin Weijun
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bingshe, X., Xuguang, L., Xiaoqin, Y. et al. Studies on the Interaction of Water-Soluble Fullerols with BSA and the Effects of Metallic Ions. MRS Online Proceedings Library 675, 741 (2001). https://doi.org/10.1557/PROC-675-W7.4.1

Download citation

  • Published:

  • DOI: https://doi.org/10.1557/PROC-675-W7.4.1

Search

Navigation