Abstract
A correction to: Bonnie R Joubert, Ethan M Lange, Nora Franceschini, Victor Mwapasa, Kari E North, Steven R Meshnick andthe NIAID Center for HIV/AIDS Vaccine Immunology. A whole genome association study of mother-to-child transmission of HIV in Malawi. Genome Medicine 2010, 2:17.
We wish to report some corrections to our study [1], none of which alters the interpretation of the data or the conclusions drawn. After publication of this work we noted that the sample size required further clarification.
Results
A total of 246 infants (114 cases, 132 controls; 116 males, 121 females, 9 with imputed gender) passed laboratory quality control. Statistical quality control removed 15 individuals for low genotyping, resulting in a total of 231 individuals (103 cases, 128 controls; 114 males, 117 females). Of the 655,352 SNPs tested, 68,297 failed statistical quality control due to HWE P < 0.001 in the controls (N = 431), low genotyping rate (N = 21,589), or for MAF < 0.01 (N = 53,477), where some overlap of SNPs across exclusion criteria existed. Results were presented for 587,055 SNPs.
References
Joubert Bonnie R, Lange Ethan M, Franceschini Nora, Mwapasa Victor, North Kari E, Meshnick Steven R, the NIAID Center for HIV/AIDS Vaccine Immunology: A whole genome association study of mother-to-child transmission of HIV in Malawi. Genome Medicine. 2010, 2: 17-
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The online version of the original article can be found at 10.1186/gm138
Electronic supplementary material
13073_2010_197_MOESM1_ESM.DOCX
Additional file 1: A Word document giving effect estimates for top SNPs of interest, by mode of transmission. The data provided represent the genome-wide association analysis by mode of HIV transmission. (DOCX 17 KB)
13073_2010_197_MOESM2_ESM.DOCX
Additional file 2: A Word document giving effect estimates for SNPs near or within genes associated with HIV/AIDS. The data provided represent the genome-wide association analysis for specific regions that have previously demonstrated association with HIV/AIDS, described in the Introduction section. (DOCX 73 KB)
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Joubert, B.R., Lange, E.M., Franceschini, N. et al. Erratum to: A whole genome association study of mother-to-child transmission of HIV in Malawi. Genome Med 2, 76 (2010). https://doi.org/10.1186/gm197
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DOI: https://doi.org/10.1186/gm197