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Genetic predisposition to helminthiases

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Russian Journal of Genetics: Applied Research

Abstract

Helminths have accompanied mankind since the earliest periods of its formation, parasites and humans have been coevolving for a long time and it is considered that it was helminths that played an important selective role in evolution of genes of the human immune system. The article presents the data on the genetic contribution to the intensity and clinical course of helminth infections in different populations, including the results of genome-wide association studies, and discusses the concept of commonality of genes of susceptibility to helminthiases and allergic diseases.

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Authors and Affiliations

  1. Central Research Laboratory, Siberian State Medical University, Ministry of Health of the Russian Federation, tr. Moskovskiy 2, Tomsk, 634050, Russia

    I. V. Saltykova & L. M. Ogorodova

  2. Laboratory of Population Genetics, Institute of Medical Genetics, Siberian Branch of Russian Academy of Medical Sciences, nab. r. Ushayki 10, Tomsk, 634050, Russia

    M. B. Freydin & V. P. Puzyrev

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  1. I. V. Saltykova
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  2. M. B. Freydin
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  3. L. M. Ogorodova
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  4. V. P. Puzyrev
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Correspondence to I. V. Saltykova.

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Original Russian Text © I.V. Saltykova, M.B. Freydin, L.M. Ogorodova, V.P. Puzyrev, 2013, published in Ekologicheskaya Genetika, 2013, Vol. 11, No. 2, pp. 22–33.

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Saltykova, I.V., Freydin, M.B., Ogorodova, L.M. et al. Genetic predisposition to helminthiases. Russ J Genet Appl Res 4, 405–415 (2014). https://doi.org/10.1134/S2079059714050128

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