Skip to main content
SpringerLink
Log in

The immunization with peptide 189–205, a derivative of serotonin receptor subtypes 1B, changes the sensetivity of adenylyl cyclase to hormones in the rat brain

  • Biochemistry, Biophysics and Molecular Biology
  • Published:
Doklady Biochemistry and Biophysics Aims and scope Submit manuscript

Abstract

The aim of this work was to study the effect of multiple (during 12 months) immunization of rats with BSA-conjugated peptide 189–205 corresponding to the second extracellular loop of rat HT1BR on ACSS activity in the brain of immunized animals (group HT1BR) and its regulation by hormones.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Wacker, D., Wang, C., Katritch, V., et al., Science, 2013, vol. 340, pp. 615–619.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  2. Svenningsson, P., Chergui, K., Rachleff, I., et al., Sci-ence, 2006, vol. 311, pp. 77–80.

    Article  CAS  Google Scholar 

  3. Rocha, B.A., Scearce-Levie, K., Lucas, J.J., et al., Nature, 1998, vol. 393, pp. 175–178.

    Article  CAS  PubMed  Google Scholar 

  4. Shpakov, A.O., Ross. Fiziol. Zh. im. I.M. Sechenova, 2011, vol. 97, no. 5, pp. 441–458.

    CAS  PubMed  Google Scholar 

  5. Shpakova, E.A., Derkach, K.V., and Shpakov, A.O., Byull. Eksp. Biol. Med., 2013, vol. 156, no. 11, pp. 603–607.

    Google Scholar 

  6. Shpakov, A.O., Shpakova, E.A., Tarasenko, I.I., et al., Int. J. Pept. Res. Ther., 2010, vol. 16, pp. 95–105.

    Article  CAS  Google Scholar 

  7. Shpakov, A.O., Chistyakova, O.V., Derkach, K.V., et al., Centr. Eur. J. Biol., 2012, vol. 7, pp. 33–47.

    CAS  Google Scholar 

  8. Bauer, M., Heinz, A., and Whybrow, P.C., Mol. Psych., 2002, vol. 7, pp. 140–156.

    Article  CAS  Google Scholar 

  9. Lifschytz, T., Gur, E., Lerer, B., and Newman, M.E., J. Neurosci. Meth., 2004, vol. 140, pp. 133–139.

    Article  CAS  Google Scholar 

  10. Dennis, R.L. and Cheng, H.W., Poultry. Sci., 2012, vol. 91, pp. 817–822.

    Article  CAS  Google Scholar 

  11. Kriem, B., Abraini, J.H., and Rostain, J.C., Pharma-col. Biochem. Behav., 1996, vol. 53, pp. 257–264.

    Article  CAS  Google Scholar 

  12. Montañez, S., Munn, J.L., Owens, W.A., et al., Neuro-chem. Int., 2014, vol. 73, pp. 127–131.

    Article  Google Scholar 

  13. Stenfors, C., Ahlgren, C., Yu, H., et al., Psychopharma-cology, 2004, vol. 172, pp. 333–340.

    Article  CAS  Google Scholar 

  14. Muñoz-Acedo, G. and Arilla, E., Brain Res. Mol. Brain Res., 1996, vol. 37, pp. 259–266.

    Article  PubMed  Google Scholar 

  15. Hazama, K., Hayata-Takano, A., Uetsuki, K., et al., PLoS One, 2014, vol. 9, p. e89153.

    Article  PubMed Central  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Morisa Toreza 44, St. Petersburg, 194223, Russia

    K. V. Derkach, E. A. Shpakova, I. I. Tarasenko, O. A. Zharova & A. O. Shpakov

Authors
  1. K. V. Derkach
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. A. Shpakova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. I. I. Tarasenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. O. A. Zharova
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. O. Shpakov
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to E. A. Shpakova.

Additional information

Original Russian Text © K.V. Derkach, E.A. Shpakova, I.I. Tarasenko, O.A. Zharova, A.O. Shpakov, 2015, published in Doklady Akademii Nauk, 2015, Vol. 463, No. 3, pp. 354–357.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Derkach, K.V., Shpakova, E.A., Tarasenko, I.I. et al. The immunization with peptide 189–205, a derivative of serotonin receptor subtypes 1B, changes the sensetivity of adenylyl cyclase to hormones in the rat brain. Dokl Biochem Biophys 463, 225–228 (2015). https://doi.org/10.1134/S1607672915040079

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1607672915040079

Keywords

Search

Navigation