Abstract
N-(Trifluoromethylsulfonyl) and N-arylsulfonyl polychloroacetaldehyde imines reacted with pyrrole, 1-alkyl-, 1-benzyl-, and 1-(4-nitrophenyl)-substituted pyrroles, and bis-pyrroles to give the corresponding 2-[1-(sulfonylamino)polychloroethyl]-1H-pyrroles or mixtures of 2- and 3-[1-(sulfonylamino)polychloroethyl]-1H-pyrroles, depending on the nature of the Schiff base and substituent on the pyrrole nitrogen atom and reaction conditions. The first synthesis of 2,5-disubstituted NH-pyrrole by reaction of pyrrole with Schiff bases was described.
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Original Russian Text © E.V. Kondrashov, E.V. Rudyakova, G.N. Rozentsveig, I.B. Rozentsveig, K.A. Chernyshev, L.B. Krivdin, G.G. Levkovskaya, 2009, published in Zhurnal Organicheskoi Khimii, 2009, Vol. 45, No. 9, pp. 1379–1387.
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Kondrashov, E.V., Rudyakova, E.V., Rozentsveig, G.N. et al. C-amidoalkylation of pyrroles with N-trifluoromethylsulfonyl and N-arylsulfonyl polychloroaldehyde imines. Russ J Org Chem 45, 1365–1374 (2009). https://doi.org/10.1134/S1070428009090097
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DOI: https://doi.org/10.1134/S1070428009090097