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A novel approach to obtain 3-amino-1-benzothiophene-2-carbonitriles

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Chemistry of Heterocyclic Compounds Aims and scope

A simple one-step protocol for the synthesis of 3-amino-1-benzothiophene-2-carbonitriles from commercially or synthetically readily available S-(cyanomethyl) O-ethyl carbodithionate and 2-fluorobenzonitriles was developed.

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The study was carried out with financial support from the Russian Science Foundation within the framework of scientific project No. 20-73-10195.

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Authors and Affiliations

  1. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St, Moscow, 117997, Russia

    Dmitry S. Ivanov, Anatolii I. Sokolov, Alexander Yu. Smirnov & Mikhail S. Baranov

  2. Pirogov Russian National Research Medical University, 1 Ostrovityanova St, Moscow, 117997, Russia

    Anatolii I. Sokolov, Alexander Yu. Smirnov & Mikhail S. Baranov

Authors
  1. Dmitry S. Ivanov
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  2. Anatolii I. Sokolov
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  3. Alexander Yu. Smirnov
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  4. Mikhail S. Baranov
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Corresponding author

Correspondence to Dmitry S. Ivanov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2024, 60(1/2), 99–102

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Ivanov, D.S., Sokolov, A.I., Smirnov, A.Y. et al. A novel approach to obtain 3-amino-1-benzothiophene-2-carbonitriles. Chem Heterocycl Comp 60, 99–102 (2024). https://doi.org/10.1007/s10593-024-03299-y

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  • DOI: https://doi.org/10.1007/s10593-024-03299-y

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