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Reaction of furan-2(3H)-ones with 1,2-binucleophiles

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Abstract

Reactions of 5-substituted furan-2(3H)-ones with ethylenediamine, 2-aminoethanol, and o-aminophenol do not stop at the stage of formation of the corresponding 4-oxoalkanoic acid amides but lead to new bi-and tricyclic structures as a result of double intramolecular cyclodehydration.

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References

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Original Russian Text © O.A. Amal’chieva, A.Yu. Egorova, 2006, published in Zhurnal Organicheskoi Khimii, 2006, Vol. 42, No. 9, pp. 1358–1361.

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Amal’chieva, O.A., Egorova, A.Y. Reaction of furan-2(3H)-ones with 1,2-binucleophiles. Russ J Org Chem 42, 1340–1343 (2006). https://doi.org/10.1134/S1070428006090144

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  • DOI: https://doi.org/10.1134/S1070428006090144

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