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Optimization of rheological properties of an adsorption vaginal gel based on Carbopol

  • Macromolecular Compounds and Polymeric Materials
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Abstract

Rheological properties of adsorption vaginal gels based on Carbopol were examined and compared with those of Metrogyl (USA). The formulation was optimized by the method of dynamic rheology, and the rheological extrusion optimum of the vaginal preparation was determined. The activation parameters of the formulations were calculated.

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References

  1. Sjoberg, M., Bergstrom, L., Jarsson, A., and Sjostrom, E., Colloids Surf. A: Physicochem. Eng. Aspects, 1999, vol. 159, pp. 197–208.

    Article  CAS  Google Scholar 

  2. Bremecker, K.D., Koch, B., Krause, W., and Neuenroth, L., Pharm. Ind., 1992, vol. 54, pp. 182–185.

    CAS  Google Scholar 

  3. Kim, J.Y., Song, J.Y., Lee, E.I., and Park, S.K., Colloid Polym. Sci., 2003, vol. 281, pp. 614–623.

    Article  CAS  Google Scholar 

  4. Lyapunov, N.A. and Volovik, N.V., Farmakom, 2001, no. 2, pp. 1–10.

  5. Tamburic, S. and Craig, D.Q.M., Pharm. Sci., 1995, no. 1, pp. 107–109.

  6. Tamburic, S. and Craig, D.Q.M., J. Control. Rel., 1995, vol. 37, pp. 59–68.

    Article  CAS  Google Scholar 

  7. Pertsev, I.M., Arkusha, A.A., and Gun’ko, V.G., in Fiziko-khimicheskaya mekhanika dispersnykh sistem i materialov (Physicochemical Mechanics of Disperse Systems and Materials), Kiev: Naukova Dumka, 1983, part 2, pp. 262–263.

    Google Scholar 

  8. Sangalov, Yu.A., Romanko, T.V., and Katsyutsevich, E.V., in Reologiya polimernykh entomologicheskikh sostavov: Trudy 17-go Mezhdunarodnogo simpoziuma po reologii (Rheology of Polymeric Entomological Formulations: Proc. 17th Int. Symp. on Rheology), Saratov, 1994, pp. 130–131.

  9. Sangalov, Yu.A., Romanko, T.V., Ponedel’kina, I.Yu., and Katsyutsevich, E.V., Kolloidn. Zh., 1995, vol. 57, no. 5, pp. 734–738.

    Google Scholar 

  10. USSR Inventor’s Certificate no. 1769830.

  11. Tager, A.A. and Botvinnik, O.G., Vysokomol. Soedin., Ser. A, 1974, vol. 16, no. 6, pp. 1284–1287.

    CAS  Google Scholar 

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Authors and Affiliations

  1. Institute of Organic Chemistry, Ufa Scientific Center, Russian Academy of Sciences, Ufa, Bashkortostan, Russia

    T. V. Romanko & Yu. I. Murinov

  2. Bashkir State Pedagogical University, Ufa, Bashkortostan, Russia

    V. G. Romanko

Authors
  1. T. V. Romanko
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  2. Yu. I. Murinov
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  3. V. G. Romanko
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Original Russian Text © T.V. Romanko, Yu.I. Murinov, V.G. Romanko, 2009, published in Zhurnal Prikladnoi Khimii, 2009, Vol. 82, No. 8, pp. 1389–1393.

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Romanko, T.V., Murinov, Y.I. & Romanko, V.G. Optimization of rheological properties of an adsorption vaginal gel based on Carbopol. Russ J Appl Chem 82, 1488–1493 (2009). https://doi.org/10.1134/S107042720908031X

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  • DOI: https://doi.org/10.1134/S107042720908031X

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