Skip to main content
SpringerLink
Log in

Synthesis, Structure, and Biological Activity of Coordination Compounds of Cobalt(II), Nickel(II), and Copper(II) with N-(Methoxyphenyl)-2-[(5-nitrofuryl)methylene]hydrazine Carbothioamides

  • Published:
Russian Journal of General Chemistry Aims and scope Submit manuscript

Abstract

4-(2-Methoxyphenyl)-, 4-(3-methoxyphenyl)-, and 4-(4-memoxyphenyl)-2-[(5-mttofuryl)methylene]-hydrazine carboxamide (HL1–3) react with hydrates of cobalt (nickel, copper) chloride (nitrate, acetate) with the formation of the M(HL1–3)2X2 (M = Co2+, Ni2+, Cu2+; X = Cl−, NO3−) and M(L1–3)2 (M = Ni2+, Cu2+) coordination compounds. Structure of the obtained compounds has been studied by means of X-ray diffraction analysis. Their antimicrobial and antifungal activity towards a series of Staphylococcus aureus, Escherichia coli, and yeast-like fungi standard strains has been investigated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Mashkovskii, M.D., Lekarstvennye sredstva, (Drugs), Moscow: Novaya Volna 2012.

    Google Scholar 

  2. Kalinowski, D.S. and Richardson, D.R., Pharmacol. Rev, 2005, vol. 57, no. 4, p. 547. doi https://doi.org/10.1124/pr.57.4.2

    Article  CAS  PubMed  Google Scholar 

  3. Beraldo, H. and Gambino, D., Mini-Rev. Med. Chem., 2004, vol. 4, no. 1, p. 31. doi https://doi.org/10.2174/1389557043487484

    Article  CAS  PubMed  Google Scholar 

  4. Ulkuseven, B., Bal-Demirci, T., Akkurt, M., Yalcin, S.P., and Buyukgungor, O., Polyhedron, 2008, vol. 27, p. 3646. doi https://doi.org/10.1016/j.poly.2008.08.024

    Article  CAS  Google Scholar 

  5. Gulea, A.P., Lozan-Tyrshu, K.S., Tapcov, V.I., Korzha, I.D., and Rudik, V.F., Russ. J. Gen. Chem, 2012, vol. 82, no. 11, p. 1869. doi https://doi.org/10.1134/S1070363212110242

    Article  CAS  Google Scholar 

  6. Spek, A.L., J. Appl. Cryst., 2003, vol. 36, p. 7. doi https://doi.org/10.1107/S0021889802022112

    Article  CAS  Google Scholar 

  7. Nakamoto, K., Infrared Spectra of Inorganic and Coordination Compounds, New York: Wiley Interscience, 1963.

    Google Scholar 

  8. Gulea, A.P., Spynu, S.N., Tsapkov, V.I., and Poirier, D., Russ. J. Gen. Chem., 2008, vol. 78, no. 8, p. 984. doi https://doi.org/10.1134/S1070363208050253

    Article  CAS  Google Scholar 

  9. Gulea, A.P., Prisacari, V.I., Tsapkov, V.I., Buracheva, S.A., Spynul, S.N., Bezhenari, N.P., Poirier, D., and Roy, J., Pharm. Chem. J., 2007, vol. 41, no. 11, p. 596. doi https://doi.org/10.30906/0023-1134-2007-41-11-29-32

    Article  CAS  Google Scholar 

  10. Gulea, A.P., Prisacari, V.I., Tsapkov, V.I., Buracheva, S.A., Spynu, S.N., and Bezhenari, N.P., Pharm. Chem. J., 2008, vol. 42, no. 11, p. 326. doi https://doi.org/10.30906/0023-1134-2008-42-6-19-21

    Article  CAS  Google Scholar 

  11. Pahontu, E., Fala, V., Gulea, A., Poirier, D., Tsapkov, V., and Rosu, T., Molecules, 2013, no. 18, p. 8812. doi https://doi.org/10.3390/molecules18088812

  12. Pahontu, E., Julea, F., Rosu, T., Purcarea, V., Chumakov, Yu., Petrenko, P., and Gulea, A., J. Cell. Mol. Med., 2015, vol. 19, no. 4, p. 865. doi https://doi.org/10.1111/jcmm.12508

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Pathan, A.H., Bakale, R.P., Naik, G.N., Frampton, C.S., and Gudasi, K.B., Polyhedron, 2012, vol. 34, no. 1, p. 149. doi https://doi.org/10.1016/j.poly.2011.12.033

    Article  CAS  Google Scholar 

  14. CrysAlisPro, Version 1.171.33.52 (release 06-11-2009 CrysAlis171.NET). Oxford Diffraction Ltd.

  15. Sheldrich, G.M., Acta Cryst. (A), 2008, vol. 64, p. 112. doi https://doi.org/10.1107/S0108767307043930

    Article  CAS  Google Scholar 

  16. Macrae, C.F., Edgington, P.R., McCabe, P., Pidcock, E., Shields, G.P., Taylor, R., Towler, M., and Van De Streek, J., J. Appl. Cryst., 2006, vol. 39, p. 453. doi https://doi.org/10.1107/S002188980600731X

    Article  CAS  Google Scholar 

  17. Saswati, Dinda, R., Schmiesing, C., Sinn, E., Patil, Y.P., Nethaji, M., Stoeckli-Evans, H., and Acharyya, R., Polyhedron, 2013, vol. 50, p. 354. doi https://doi.org/10.1016/j.poly.2012.11.031

    Article  CAS  Google Scholar 

  18. Gulea, A., Poirier, D., Roy, J., Stavila, V., Bulimestru, I., Tapcov, V., Birca, M., and Popovschi, L., J. Enzyme Inhib. Med. Chem., 2008, vol. 23, no. 6, p. 806. doi 101080/147563607017443002

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. State University of Moldova, ul. Mateevicha 60, Kishinev, Moldova

    A. P. Gulea, N. L. Mitkevich & V. I. Tsapkov

  2. Institute of Applied Physics, Kishinev, Moldova

    Yu. M. Chumakov & P. A. Petrenko

  3. Gebze Institute of Technology, Cayirova, Kocaeli, Turkey

    Yu. M. Chumakov

  4. State University of Medicine and Pharmacy “Nicolae Testemitanu,”, Kishinev, Moldova

    G. G. Balan & O. S. Burduniuc

  5. National Agency of Public Health, Kishinev, Moldova

    O. S. Burduniuc

Authors
  1. A. P. Gulea
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. L. Mitkevich
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yu. M. Chumakov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. P. A. Petrenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. G. G. Balan
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. O. S. Burduniuc
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. V. I. Tsapkov
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to V. I. Tsapkov.

Additional information

Russian Text © The Author(s), 2019, published in Zhurnal Obshchei Khimii, 2019, Vol. 89, No. 7, pp. 1058–1068.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gulea, A.P., Mitkevich, N.L., Chumakov, Y.M. et al. Synthesis, Structure, and Biological Activity of Coordination Compounds of Cobalt(II), Nickel(II), and Copper(II) with N-(Methoxyphenyl)-2-[(5-nitrofuryl)methylene]hydrazine Carbothioamides. Russ J Gen Chem 89, 1415–1423 (2019). https://doi.org/10.1134/S1070363219070119

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070363219070119

Keywords

Search

Navigation