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Comparative analysis of the effectiveness of STR and SNP markers for intraspecific and interspecific differentiation of the genus Ovis

  • Animal Genetics
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Abstract

A comparative study of the informativeness of SNP and STR markers for interspecific and intraspecific differentiation of the two species of the genus Ovis, snow sheep (O. nivicola) and domestic sheep (O. aries), was conducted. Eleven STR loci combined into two multiplex panels were examined. SNP analysis was performed with the DNA microarray OvineSNP50K BeadChip featuring 54241 SNPs. The possibility of clear differentiation of the studied Ovis species with both types of genetic markers was demonstrated. The advantages of SNP markers for intraspecific differentiation of the O. aries breeds and O. nivicola geographical groups were revealed. The areas of application of the studied types of DNA markers are discussed.

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Authors and Affiliations

  1. Ernst All-Russia Research Institute for Animal Husbandry, Dubrovitsy settlement, Moscow oblast, 142132, Russia

    T. E. Deniskova, A. A. Sermyagin, V. A. Bagirov, I. M. Okhlopkov, E. A. Gladyr, R. V. Ivanov, G. Brem & N. A. Zinovieva

  2. Institute for Biological Problems of Cryolithozone, Siberian Branch of the Russian Academy of Sciences, Yakutsk, 677890, Russia

    I. M. Okhlopkov

  3. Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Vienna, A-1210, Austria

    G. Brem

Authors
  1. T. E. Deniskova
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  2. A. A. Sermyagin
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  3. V. A. Bagirov
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  4. I. M. Okhlopkov
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  5. E. A. Gladyr
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  6. R. V. Ivanov
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  7. G. Brem
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  8. N. A. Zinovieva
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Correspondence to T. E. Deniskova.

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Original Russian Text © T.E. Deniskova, A.A. Sermyagin, V.A. Bagirov, I.M. Okhlopkov, E.A. Gladyr, R.V. Ivanov, G. Brem, N.A. Zinovieva, 2016, published in Genetika, 2016, Vol. 52, No. 1, pp. 90–96.

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Deniskova, T.E., Sermyagin, A.A., Bagirov, V.A. et al. Comparative analysis of the effectiveness of STR and SNP markers for intraspecific and interspecific differentiation of the genus Ovis . Russ J Genet 52, 79–84 (2016). https://doi.org/10.1134/S1022795416010026

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  • DOI: https://doi.org/10.1134/S1022795416010026

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