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Cardiovascular effects of nerve growth factor: An analytical review. Part II

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Abstract

The features of NGF’s influence on the functional activity of the cardiovascular system and the signaling pathways by which activated NGF TrkA and p75ntr receptors regulate the functional state of endothelial and vascular smooth muscle cells and cardiomyocytes are discussed. In addition, the theoretical prospects of agonists and antagonists of TrkA and p75ntr receptors for the treatment of heart and vascular disorders are considered.

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  1. Zakusov Institute of Pharmacology, Russian Academy of Sciences, Moscow, 125315, Russia

    S. A. Kryzhanovskii & M. B. Vititnova

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Original Russian Text © S.A. Kryzhanovskii, M.B. Vititnova, 2011, published in Fiziologiya Cheloveka, 2011, Vol. 37, No. 3, pp. 109–128.

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Kryzhanovskii, S.A., Vititnova, M.B. Cardiovascular effects of nerve growth factor: An analytical review. Part II. Hum Physiol 37, 361–378 (2011). https://doi.org/10.1134/S0362119711030066

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