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Silver Nanoparticles Stabilized with Chitosan Succinamide: Synthesis and Antibacterial Activity

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Abstract

A water-soluble chitosan derivative, chitosan succinamide, was used as a polymer matrix for the formation of silver nanoparticles via ion reduction under microwave irradiation in the presence of a D-glucose reducing agent. UV spectroscopy confirmed the presence of silver nanoparticles in the synthesized colloidal solution. Transmission electron microscopy showed that the synthesized silver nanoparticles had a spherical shape. The obtained diffractograms confirm the presence of reflexes characteristic of the crystal lattice of metallic silver. In vitro studies showed that the synthesized colloidal solution of silver nanoparticles exhibits pronounced antibacterial activity against strains of the gram-positive bacteria Bacillus subtilis ATCC 6633 and Bacillus coagulans 429.

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This work was carried out as part of the state task of the Institute of Chemical Economy of the Russian Academy of Sciences.

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Correspondence to V. A. Alexandrova or A. M. Futoryanskaya.

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The authors declare that they have no conflict of interest. This article does not contain any studies involving animals or human participants performed by any of the authors.

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Alexandrova, V.A., Futoryanskaya, A.M. & Sadykova, V.S. Silver Nanoparticles Stabilized with Chitosan Succinamide: Synthesis and Antibacterial Activity. Appl Biochem Microbiol 56, 590–594 (2020). https://doi.org/10.1134/S0003683820050026

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