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ATP, Activation, and the Heat of Shortening of Muscle

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An Erratum to this article was published on 01 November 1967

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Abstract

Prof. A. V. Hill has challenged biochemists to find whether the heat of shortening of muscle has any equivalent in the chemistry of muscle. It is shown that the heat of shortening, which is reabsorbed as tension disappears, is not degraded free energy from the splitting of ATP. It must be reversibly transformed entropy from a repeated cyclic reaction such as coil-helix transitions in part of the myosin–actin cross bridges.

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  • 01 November 1967

    Professor R. E. Davies, of the University of Pennsylvania (School of Veterinary Medicine), has written to the Editor to complain that the words "Professor A. V. Hill's Further Challenge to Biochemists" were omitted from the title of his article, "ATP, Activation, and the Heat of Shortening of Muscle", published in Nature, 214, 148 (1967).

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Authors and Affiliations

  1. Laboratories of Biochemistry, Department of Animal Biology, School of Veterinary Medicine, and Graduate Group on Molecular Biology, University of Pennsylvania, Philadelphia, Pennsylvania

    R. E. DAVIES, M. J. KUSHMERICK & R. E. LARSON

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  1. R. E. DAVIES
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  2. M. J. KUSHMERICK
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  3. R. E. LARSON
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DAVIES, R., KUSHMERICK, M. & LARSON, R. ATP, Activation, and the Heat of Shortening of Muscle. Nature 214, 148–151 (1967). https://doi.org/10.1038/214148a0

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