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Synthesis of 2-Methyl-4-quinolyl Isothiocyanate

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Abstract

A procedure has been developed for the synthesis of substituted 2-methylquinolin-4-ylthiuronium salts by reaction of 2-methyl-4-chloroquinoline with N-substituted thioureas. Alkaline hydrolysis of these salts yields 2-methyl-4-quinolyl isothiocyanate instead of the expected 2-methylquinoline-4-thiol.

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Authors and Affiliations

  1. Erevan State University, ul. Aleka Manukyana 1, Erevan, 375025, Armenia

    A. A. Avetisyan, I. L. Aleksanyan & L. P. Ambartsumyan

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  1. A. A. Avetisyan
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  2. I. L. Aleksanyan
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  3. L. P. Ambartsumyan
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Avetisyan, A.A., Aleksanyan, I.L. & Ambartsumyan, L.P. Synthesis of 2-Methyl-4-quinolyl Isothiocyanate. Russian Journal of Organic Chemistry 40, 407–408 (2004). https://doi.org/10.1023/B:RUJO.0000034979.97653.de

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  • DOI: https://doi.org/10.1023/B:RUJO.0000034979.97653.de

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