Skip to main content
SpringerLink
Log in

Typical Changes of Erythrocytes in Chronic Inflammation

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Structural and metabolic status and function of erythrocytes were studied in patients with chronic bronchitis, chronic inflammatory diseases of the upper airways, and chronic colitis. Complex study of the peripheral component of the erythron showed that disorders in erythrocyte morphology and function (decreased erythrocyte dry weight, low concentration of sulfhydryl groups and lipoproteins, decreased content of high molecular weight polypeptides in parallel with increased content of low molecular weight proteins, increased number of transformed cells, and enhanced reversible aggregation) were nonspecific and did not depend on the location of the inflammatory process.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. V. V. Novitskii, N. V. Ryazantseva, E. A. Stepovaya, et al., Atlas. Clinical Pathomorphosis of Erythrocyte [in Russian], Tomsk (2003).

  2. Yu. A. Vladimirov, Pat. Fiziol. Eksper. Ter., No. 4, 7–19 (1989).

  3. V. E. Gol'dberg, A. M. Dygai, and V. V. Novitskii, Lung Cancer and Blood System [in Russian], Tomsk (1992).

  4. A. M. Dygai and N. A. Klimenko, Inflammation and Hemopoiesis [in Russian], Tomsk (1992).

  5. G. I. Kozinets and Yu. A. Simovart, Surface Architectonics of Peripheral Blood Cells in Health and Blood System Diseases [in Russian], Tallinn (1984).

  6. D. N. Mayanskii and I. G. Ursov, Lectures in Clinical Pathology: Manual for Physicians [in Russian], Novosibirsk (1997).

  7. G. I. Kozinets, I. A. Bykova, T. A. Mamedova, et al., Method for Interferometry in Hematology. Methodological Recommendations [in Russian], Moscow (1980).

  8. S. A. Storozhok, A. G. Sannikov, and Yu. M. Zakharov, Molecular Structure of Erythrocyte Membranes and Their Mechanical Characteristics [in Russian], Tyumen (1997).

  9. R. T. Tukhvatulin, V. A. Levtov, V. N. Shuvaeva, et al., Fiziol. Zh., 72, No. 6, 775–784 (1986).

    Google Scholar 

  10. Erythrocytes and Malignant Tumors, Eds. V. V. Novitskii et al. [in Russian], Tomsk (2000).

  11. M. C. Barenbaum, Nature, 174, 190–195 (1956).

    Google Scholar 

  12. M. Chevremont and J. Frederick, Arch. Biol. Liege, 54, 589–593 (1943).

    Google Scholar 

  13. J. T. Dodge, C. Mitchell, D. J. Hanahan, et al., Arch. Biochem. Biophys., 100, No. 1, 119–130 (1963).

    Google Scholar 

  14. U. K. Laemmli, Nature, 227, No. 5259, 680–689 (1970).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Ministry of Health of Russian Federation, Siberian State Medical University, Moscow

    E. A. Stepovaya, V. V. Novitskii, N. V. Ryazantseva, S. B. Tkachenko & V. E. Gol'dberg

Authors
  1. E. A. Stepovaya
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. V. Novitskii
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. V. Ryazantseva
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. S. B. Tkachenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. V. E. Gol'dberg
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Stepovaya, E.A., Novitskii, V.V., Ryazantseva, N.V. et al. Typical Changes of Erythrocytes in Chronic Inflammation. Bulletin of Experimental Biology and Medicine 137, 56–60 (2004). https://doi.org/10.1023/B:BEBM.0000024387.17208.c4

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:BEBM.0000024387.17208.c4

Search

Navigation