Abstract
The effect of MeSnCl3, which is a highly toxic compound, on the activity of L-lactate:NAD oxidoreductase (lactate dehydrogenase) in the extract from the liver of Russian sturgeon (Asipenser gueldenstaedtiB.). Noncompetitive inhibition of the enzymatic reaction was discovered. This can be due to a change in the enzyme conformation caused by the action on the thiol groups, important for enzyme activity.
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Kolyada, M.N., Pimenov, Y.T., Berberova, N.T. et al. Effect of methyltin trichloride on the activity of lactate dehydrogenase. Russian Chemical Bulletin 50, 1485–1488 (2001). https://doi.org/10.1023/A:1012765930333
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DOI: https://doi.org/10.1023/A:1012765930333