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Influence of Polyuronides on Biological Oxidation, Liver Antitoxic Functions, and Erythrocyte Membrane Condition in Lead-Intoxicated Rats

  • MOLECULAR-BIOLOGICAL PROBLEMS OF DRUG DESIGN AND MECHANISM OF DRUG ACTION
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Pharmaceutical Chemistry Journal Aims and scope

The influence of pectin and laminarid NP complex on biological oxidation processes in lead-intoxicated rats was estimated using parameters such as oxidative phosphorylation, ATP synthesis, activities of biological oxidation enzymes, lipid peroxidation, and erythrocyte resistance to osmotic shock and oxidation by oxygen in air, liver antitoxic function, and blood hematological indices. It was established that the polyuronides exhibited antihypoxic, antioxidant, and membrane-stabilizing action.

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Authors and Affiliations

  1. Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University, Russian Ministry of Health, Stavropol’skii Krai, Pyatigorsk, 357532, Russia

    N. Sh. Kaisheva, Yu. K. Vasilenko & A. Sh. Kaishev

Authors
  1. N. Sh. Kaisheva
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  2. Yu. K. Vasilenko
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  3. A. Sh. Kaishev
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Correspondence to N. Sh. Kaisheva.

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 50, No. 10, pp. 3 – 9, October, 2016.

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Kaisheva, N.S., Vasilenko, Y.K. & Kaishev, A.S. Influence of Polyuronides on Biological Oxidation, Liver Antitoxic Functions, and Erythrocyte Membrane Condition in Lead-Intoxicated Rats. Pharm Chem J 50, 631–636 (2017). https://doi.org/10.1007/s11094-017-1504-8

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  • DOI: https://doi.org/10.1007/s11094-017-1504-8

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