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Neuroleptic malignant syndrome during zuclopenthixol therapy in X-linked cerebral adrenoleukodystrophy

  • Published:
Journal of Inherited Metabolic Disease

Abstract

An 8 year-old boy with X-ALD under treatment with simvastatin developed a severe adverse reaction when the dose of his other medication, zuclopenthixol was increased. Both drugs were withdrawn after a diagnosis of neuroleptic malignant syndrome was made.

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REFERENCES

  • Deslypere JP, Vermeulen A (1991) Rhabdomyolysis and simvastatin. Ann Intern Med 114: 342.

    Google Scholar 

  • Gurrera RJ (1999) Sympathoadrenal hyperactivity and the etiology of neuroleptic malignant syndrome. Am J Psychiatry 156: 169-180.

    Google Scholar 

  • Verrips A, Willemsen MA, Rubio-Gozalbo E, De Jong J, Smeitink JA (2000) Simvastatin and plasma very-long-chain fatty acids in X-linked adrenoleukodystrophy. Ann Neurol 47: 552-553.

    Google Scholar 

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Authors and Affiliations

  1. Department of Paediatrics, University Hospital Maastricht, The Netherlands

    M. E. Rubio-Gozalbo, D. A. van Waardenburg & P. P. Forget

  2. Department of Biochemical Genetics, Stichting Klinische Genetica Z.O.N., Maastricht, The Netherlands

    L. J. M. Spaapen

  3. Department of Paediatric Neurology, University Medical Center St Radboud, Nijmegen, The Netherlands

    A. Verrips

  4. Department of Pediatric Neurology, University Hospital Maastricht, The Netherlands

    P. C. A. J. Vroomen

Authors
  1. M. E. Rubio-Gozalbo
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  2. D. A. van Waardenburg
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  3. P. P. Forget
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  4. L. J. M. Spaapen
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  5. A. Verrips
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  6. P. C. A. J. Vroomen
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Rubio-Gozalbo, M.E., van Waardenburg, D.A., Forget, P.P. et al. Neuroleptic malignant syndrome during zuclopenthixol therapy in X-linked cerebral adrenoleukodystrophy. J Inherit Metab Dis 24, 605–606 (2001). https://doi.org/10.1023/A:1012480130445

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  • DOI: https://doi.org/10.1023/A:1012480130445

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